Evidence for two active X chromosomes in a human XXY triploid

David D. Weaver, Stanley M. Gartler, André Boué, Joëlle G. Boué

Research output: Contribution to journalArticle

20 Scopus citations

Abstract

A human XXY chromatin negative triploid culture has been found to have both the A and B isozymes of glucose-6-phosphate dehydrogenase, as well as an intermediately migrating AB (hybrid) band. This finding indicates that the cells in this culture each possess 2 active X chromosomes. Possible mechanisms producing the abnormalities seen in this disorder are presented and discussed.

Original languageEnglish (US)
Pages (from-to)39-42
Number of pages4
JournalHuman genetics
Volume28
Issue number1
DOIs
StatePublished - Mar 1 1975
Externally publishedYes

    Fingerprint

ASJC Scopus subject areas

  • Genetics
  • Genetics(clinical)

Cite this