Evidence for two active X chromosomes in a human XXY triploid

David Weaver, Stanley M. Gartler, André Boué, Joëlle G. Boué

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

A human XXY chromatin negative triploid culture has been found to have both the A and B isozymes of glucose-6-phosphate dehydrogenase, as well as an intermediately migrating AB (hybrid) band. This finding indicates that the cells in this culture each possess 2 active X chromosomes. Possible mechanisms producing the abnormalities seen in this disorder are presented and discussed.

Original languageEnglish (US)
Pages (from-to)39-42
Number of pages4
JournalHuman Genetics
Volume28
Issue number1
DOIs
StatePublished - Mar 1975
Externally publishedYes

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Triploidy
Glucosephosphate Dehydrogenase
X Chromosome
Isoenzymes
Chromatin
Cell Culture Techniques

ASJC Scopus subject areas

  • Genetics(clinical)
  • Genetics
  • Medicine(all)

Cite this

Evidence for two active X chromosomes in a human XXY triploid. / Weaver, David; Gartler, Stanley M.; Boué, André; Boué, Joëlle G.

In: Human Genetics, Vol. 28, No. 1, 03.1975, p. 39-42.

Research output: Contribution to journalArticle

Weaver, David ; Gartler, Stanley M. ; Boué, André ; Boué, Joëlle G. / Evidence for two active X chromosomes in a human XXY triploid. In: Human Genetics. 1975 ; Vol. 28, No. 1. pp. 39-42.
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