Evolution of controlling diabetic retinopathy: Changing trends in the management of diabetic macular EDEMA at a single institution over the past decade

Denis Jusufbegovic, Mark O. Mugavin, Shlomit Schaal

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Purpose: To report the evolution of treatment in managing diabetic macular edema (DME) in a "real world" clinical setting. Methods: Retrospective observational case series of 1,862 patients treated for DME over the last decade. Change in selection of treatment modalities used for controlling DME, visual acuity, and degree of DME on optical coherence tomography were recorded. Results: Over the past decade, there was a linear decrease in laser use, with exponential growth in the utilization of intravitreal injections. An increase in the frequency of clinic visits from 3 ± 2 visits per year to 9 ± 2 visits per year with significant visual and anatomical improvements was noted: mean improvement in visual acuity increased from 0.01 ± 0.1 logMAR units (which is equivalent to less than 1 Snellen line) to 0.3 ± 0.2 logMAR units (which is equivalent to 2 Snellen lines) (P < 0.05), mean decrease in retinal thickness changed from 58 ± 59 m to 162 ± 91 m (P < 0.05). Conclusion: An evolution in treatment strategy for controlling DME over the last decade was reflected by the replacement of focal laser therapy with intravitreal injections. This has produced significant improvements in visual and anatomical outcomes but has increased the frequency of office visits.

Original languageEnglish (US)
Pages (from-to)929-934
Number of pages6
JournalRetina
Volume35
Issue number5
DOIs
StatePublished - May 8 2015

Fingerprint

Macular Edema
Diabetic Retinopathy
Intravitreal Injections
Visual Acuity
Office Visits
Optical Coherence Tomography
Laser Therapy
Ambulatory Care
Lasers
Therapeutics
Growth

Keywords

  • anti-VEGF
  • diabetic macular edema
  • evolution of management
  • treatment

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Evolution of controlling diabetic retinopathy : Changing trends in the management of diabetic macular EDEMA at a single institution over the past decade. / Jusufbegovic, Denis; Mugavin, Mark O.; Schaal, Shlomit.

In: Retina, Vol. 35, No. 5, 08.05.2015, p. 929-934.

Research output: Contribution to journalArticle

@article{d1cafcea7cda49259a65935de6c7ada8,
title = "Evolution of controlling diabetic retinopathy: Changing trends in the management of diabetic macular EDEMA at a single institution over the past decade",
abstract = "Purpose: To report the evolution of treatment in managing diabetic macular edema (DME) in a {"}real world{"} clinical setting. Methods: Retrospective observational case series of 1,862 patients treated for DME over the last decade. Change in selection of treatment modalities used for controlling DME, visual acuity, and degree of DME on optical coherence tomography were recorded. Results: Over the past decade, there was a linear decrease in laser use, with exponential growth in the utilization of intravitreal injections. An increase in the frequency of clinic visits from 3 ± 2 visits per year to 9 ± 2 visits per year with significant visual and anatomical improvements was noted: mean improvement in visual acuity increased from 0.01 ± 0.1 logMAR units (which is equivalent to less than 1 Snellen line) to 0.3 ± 0.2 logMAR units (which is equivalent to 2 Snellen lines) (P < 0.05), mean decrease in retinal thickness changed from 58 ± 59 m to 162 ± 91 m (P < 0.05). Conclusion: An evolution in treatment strategy for controlling DME over the last decade was reflected by the replacement of focal laser therapy with intravitreal injections. This has produced significant improvements in visual and anatomical outcomes but has increased the frequency of office visits.",
keywords = "anti-VEGF, diabetic macular edema, evolution of management, treatment",
author = "Denis Jusufbegovic and Mugavin, {Mark O.} and Shlomit Schaal",
year = "2015",
month = "5",
day = "8",
doi = "10.1097/IAE.0000000000000438",
language = "English (US)",
volume = "35",
pages = "929--934",
journal = "Retina",
issn = "0275-004X",
publisher = "Lippincott Williams and Wilkins",
number = "5",

}

TY - JOUR

T1 - Evolution of controlling diabetic retinopathy

T2 - Changing trends in the management of diabetic macular EDEMA at a single institution over the past decade

AU - Jusufbegovic, Denis

AU - Mugavin, Mark O.

AU - Schaal, Shlomit

PY - 2015/5/8

Y1 - 2015/5/8

N2 - Purpose: To report the evolution of treatment in managing diabetic macular edema (DME) in a "real world" clinical setting. Methods: Retrospective observational case series of 1,862 patients treated for DME over the last decade. Change in selection of treatment modalities used for controlling DME, visual acuity, and degree of DME on optical coherence tomography were recorded. Results: Over the past decade, there was a linear decrease in laser use, with exponential growth in the utilization of intravitreal injections. An increase in the frequency of clinic visits from 3 ± 2 visits per year to 9 ± 2 visits per year with significant visual and anatomical improvements was noted: mean improvement in visual acuity increased from 0.01 ± 0.1 logMAR units (which is equivalent to less than 1 Snellen line) to 0.3 ± 0.2 logMAR units (which is equivalent to 2 Snellen lines) (P < 0.05), mean decrease in retinal thickness changed from 58 ± 59 m to 162 ± 91 m (P < 0.05). Conclusion: An evolution in treatment strategy for controlling DME over the last decade was reflected by the replacement of focal laser therapy with intravitreal injections. This has produced significant improvements in visual and anatomical outcomes but has increased the frequency of office visits.

AB - Purpose: To report the evolution of treatment in managing diabetic macular edema (DME) in a "real world" clinical setting. Methods: Retrospective observational case series of 1,862 patients treated for DME over the last decade. Change in selection of treatment modalities used for controlling DME, visual acuity, and degree of DME on optical coherence tomography were recorded. Results: Over the past decade, there was a linear decrease in laser use, with exponential growth in the utilization of intravitreal injections. An increase in the frequency of clinic visits from 3 ± 2 visits per year to 9 ± 2 visits per year with significant visual and anatomical improvements was noted: mean improvement in visual acuity increased from 0.01 ± 0.1 logMAR units (which is equivalent to less than 1 Snellen line) to 0.3 ± 0.2 logMAR units (which is equivalent to 2 Snellen lines) (P < 0.05), mean decrease in retinal thickness changed from 58 ± 59 m to 162 ± 91 m (P < 0.05). Conclusion: An evolution in treatment strategy for controlling DME over the last decade was reflected by the replacement of focal laser therapy with intravitreal injections. This has produced significant improvements in visual and anatomical outcomes but has increased the frequency of office visits.

KW - anti-VEGF

KW - diabetic macular edema

KW - evolution of management

KW - treatment

UR - http://www.scopus.com/inward/record.url?scp=84929049146&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84929049146&partnerID=8YFLogxK

U2 - 10.1097/IAE.0000000000000438

DO - 10.1097/IAE.0000000000000438

M3 - Article

C2 - 25590856

AN - SCOPUS:84929049146

VL - 35

SP - 929

EP - 934

JO - Retina

JF - Retina

SN - 0275-004X

IS - 5

ER -