Executive summary of the 2017 KDIGO Chronic Kidney Disease–Mineral and Bone Disorder (CKD-MBD) Guideline Update: what's changed and why it matters

Markus Ketteler, Geoffrey A. Block, Pieter Evenepoel, Masafumi Fukagawa, Charles A. Herzog, Linda McCann, Sharon Moe, Rukshana Shroff, Marcello A. Tonelli, Nigel D. Toussaint, Marc G. Vervloet, Mary B. Leonard

Research output: Contribution to journalArticle

187 Citations (Scopus)

Abstract

The KDIGO 2017 Clinical Practice Guideline Update for the Diagnosis, Evaluation, Prevention, and Treatment of CKD-MBD represents a selective update of the prior CKD-MBD Guideline published in 2009. This update, along with the 2009 publication, is intended to assist the practitioner caring for adults and children with chronic kidney disease (CKD), those on chronic dialysis therapy, or individuals with a kidney transplant. This review highlights key aspects of the 2017 CKD-MBD Guideline Update, with an emphasis on the rationale for the changes made to the original guideline document. Topic areas encompassing updated recommendations include diagnosis of bone abnormalities in CKD–mineral and bone disorder (MBD), treatment of CKD-MBD by targeting phosphate lowering and calcium maintenance, treatment of abnormalities in parathyroid hormone in CKD-MBD, treatment of bone abnormalities by antiresorptives and other osteoporosis therapies, and evaluation and treatment of kidney transplant bone disease.

Original languageEnglish (US)
Pages (from-to)26-36
Number of pages11
JournalKidney International
Volume92
Issue number1
DOIs
StatePublished - Jul 1 2017

Fingerprint

Guidelines
Bone and Bones
Therapeutics
Transplants
Kidney
Bone Diseases
Parathyroid Hormone
Chronic Renal Insufficiency
Practice Guidelines
Osteoporosis
Publications
Dialysis
Maintenance

Keywords

  • bone mineral density
  • calcium
  • dialysis
  • hyperparathyroidism
  • hyperphosphatemia
  • KDIGO CKD-MBD Guideline
  • kidney transplantation

ASJC Scopus subject areas

  • Medicine(all)
  • Nephrology

Cite this

Executive summary of the 2017 KDIGO Chronic Kidney Disease–Mineral and Bone Disorder (CKD-MBD) Guideline Update : what's changed and why it matters. / Ketteler, Markus; Block, Geoffrey A.; Evenepoel, Pieter; Fukagawa, Masafumi; Herzog, Charles A.; McCann, Linda; Moe, Sharon; Shroff, Rukshana; Tonelli, Marcello A.; Toussaint, Nigel D.; Vervloet, Marc G.; Leonard, Mary B.

In: Kidney International, Vol. 92, No. 1, 01.07.2017, p. 26-36.

Research output: Contribution to journalArticle

Ketteler, M, Block, GA, Evenepoel, P, Fukagawa, M, Herzog, CA, McCann, L, Moe, S, Shroff, R, Tonelli, MA, Toussaint, ND, Vervloet, MG & Leonard, MB 2017, 'Executive summary of the 2017 KDIGO Chronic Kidney Disease–Mineral and Bone Disorder (CKD-MBD) Guideline Update: what's changed and why it matters', Kidney International, vol. 92, no. 1, pp. 26-36. https://doi.org/10.1016/j.kint.2017.04.006
Ketteler, Markus ; Block, Geoffrey A. ; Evenepoel, Pieter ; Fukagawa, Masafumi ; Herzog, Charles A. ; McCann, Linda ; Moe, Sharon ; Shroff, Rukshana ; Tonelli, Marcello A. ; Toussaint, Nigel D. ; Vervloet, Marc G. ; Leonard, Mary B. / Executive summary of the 2017 KDIGO Chronic Kidney Disease–Mineral and Bone Disorder (CKD-MBD) Guideline Update : what's changed and why it matters. In: Kidney International. 2017 ; Vol. 92, No. 1. pp. 26-36.
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