Experimental characterization of powered Fontan hemodynamics in an idealized total cavopulmonary connection model

Anna Elodie M. Kerlo, Yann T. Delorme, Duo Xu, Steven H. Frankel, Guruprasad A. Giridharan, Mark D. Rodefeld, Jun Chen

Research output: Contribution to journalArticle

12 Scopus citations

Abstract

A viscous impeller pump (VIP) based on the Von Karman viscous pump is specifically designed to provide cavopulmonary assist in a univentricular Fontan circulation. The technology will make it possible to biventricularize the univentricular Fontan circulation. Ideally, it will reduce the number of surgeries required for Fontan conversion from three to one early in life, while simultaneously improving physiological conditions. Later in life, it will provide a currently unavailable means of chronic support for adolescent and adult patients with failing Fontan circulations. Computational fluid dynamics simulations demonstrate that the VIP can satisfactorily augment cavopulmonary blood flow in an idealized total cavopulmonary connection (TCPC). When the VIP is deployed at the TCPC intersection as a static device, it stabilizes the four-way flow pattern and is not obstructive to the flow. Experimental studies are carried out to assess performance, hemodynamic characteristics, and flow structures of the VIP in an idealized TCPC model. Stereoscopic particle image velocimetry is applied using index-matched blood analog. Results show excellent performance of the VIP without cavitation and with reduction of the energy losses. The non-rotating VIP smoothes and accelerates flow, and decreases stresses and turbulence in the TCPC. The rotating VIP generates the desired low-pressure Fontan flow augmentation (0-10 mmHg) while maintaining acceptable stress thresholds.

Original languageEnglish (US)
Article number1581
JournalExperiments in Fluids
Volume54
Issue number8
DOIs
StatePublished - Aug 1 2013

ASJC Scopus subject areas

  • Computational Mechanics
  • Mechanics of Materials
  • Physics and Astronomy(all)
  • Fluid Flow and Transfer Processes

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