Experimental characterization of powered Fontan hemodynamics in an idealized total cavopulmonary connection model

Anna Elodie M Kerlo, Yann T. Delorme, Duo Xu, Steven H. Frankel, Guruprasad A. Giridharan, Mark Rodefeld, Jun Chen

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

A viscous impeller pump (VIP) based on the Von Karman viscous pump is specifically designed to provide cavopulmonary assist in a univentricular Fontan circulation. The technology will make it possible to biventricularize the univentricular Fontan circulation. Ideally, it will reduce the number of surgeries required for Fontan conversion from three to one early in life, while simultaneously improving physiological conditions. Later in life, it will provide a currently unavailable means of chronic support for adolescent and adult patients with failing Fontan circulations. Computational fluid dynamics simulations demonstrate that the VIP can satisfactorily augment cavopulmonary blood flow in an idealized total cavopulmonary connection (TCPC). When the VIP is deployed at the TCPC intersection as a static device, it stabilizes the four-way flow pattern and is not obstructive to the flow. Experimental studies are carried out to assess performance, hemodynamic characteristics, and flow structures of the VIP in an idealized TCPC model. Stereoscopic particle image velocimetry is applied using index-matched blood analog. Results show excellent performance of the VIP without cavitation and with reduction of the energy losses. The non-rotating VIP smoothes and accelerates flow, and decreases stresses and turbulence in the TCPC. The rotating VIP generates the desired low-pressure Fontan flow augmentation (0-10 mmHg) while maintaining acceptable stress thresholds.

Original languageEnglish
Article number1581
JournalExperiments in Fluids
Volume54
Issue number8
DOIs
StatePublished - Aug 2013

Fingerprint

hemodynamics
Hemodynamics
Pumps
pumps
Blood
Flow structure
particle image velocimetry
blood flow
computational fluid dynamics
cavitation flow
Cavitation
surgery
Velocity measurement
Flow patterns
intersections
Surgery
blood
Energy dissipation
flow distribution
Computational fluid dynamics

ASJC Scopus subject areas

  • Physics and Astronomy(all)
  • Fluid Flow and Transfer Processes
  • Computational Mechanics
  • Mechanics of Materials

Cite this

Experimental characterization of powered Fontan hemodynamics in an idealized total cavopulmonary connection model. / Kerlo, Anna Elodie M; Delorme, Yann T.; Xu, Duo; Frankel, Steven H.; Giridharan, Guruprasad A.; Rodefeld, Mark; Chen, Jun.

In: Experiments in Fluids, Vol. 54, No. 8, 1581, 08.2013.

Research output: Contribution to journalArticle

Kerlo, Anna Elodie M ; Delorme, Yann T. ; Xu, Duo ; Frankel, Steven H. ; Giridharan, Guruprasad A. ; Rodefeld, Mark ; Chen, Jun. / Experimental characterization of powered Fontan hemodynamics in an idealized total cavopulmonary connection model. In: Experiments in Fluids. 2013 ; Vol. 54, No. 8.
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