Experimental studies of using of split beam transducer for prostate cancer therapy in comparison to single beam transducer

Jimmy S J Wu, Narendra T. Sanghvi, Michael H. Phillips, M. Kuznetsov, Richard Foster, Richard Bihrle, Thomas Gardner, S. I. Umemura

Research output: Chapter in Book/Report/Conference proceedingConference contribution

7 Citations (Scopus)

Abstract

A 'split beam' transducer arrangement was adapted for the existing benign prostatic hyperplasia (BPH) high intensity focused ultrasound (HIFU) treatment device, Sonablate - 200 (manufactured by Focus Surgery Inc., Indianapolis, IN) for the treatment of localized prostate cancer. In the split beam configuration the HIFU beam is divided into several beams to create a larger treatment volume per ultrasound exposure which can reduce the overall treatment time. The objective of current study was to compare the necrosis volume and temperature patterns produced from 'single beam' and 'split beam' operating configurations. Experiments were performed on different test objects including Mylar strip, plexiglass, turkey breast tissue (in-vitro) and in vivo dog prostates. The results showed that the split beam configuration created larger lesion volume for the same exposure time while keeping the temperature near the rectal wall at the safe levels. Thus split beam transducer (SBT) configuration should be effective and efficient in clinical application for the prostate cancer treatment.

Original languageEnglish (US)
Title of host publicationProceedings of the IEEE Ultrasonics Symposium
PublisherIEEE
Pages1443-1446
Number of pages4
Volume2
StatePublished - 1999
Event1999 IEEE Ultrasonics Symposium - Caesars Tahoe, NV, USA
Duration: Oct 17 1999Oct 20 1999

Other

Other1999 IEEE Ultrasonics Symposium
CityCaesars Tahoe, NV, USA
Period10/17/9910/20/99

Fingerprint

Transducers
Ultrasonics
Oncology
Surgery
Tissue
Temperature
Experiments

ASJC Scopus subject areas

  • Engineering(all)

Cite this

Wu, J. S. J., Sanghvi, N. T., Phillips, M. H., Kuznetsov, M., Foster, R., Bihrle, R., ... Umemura, S. I. (1999). Experimental studies of using of split beam transducer for prostate cancer therapy in comparison to single beam transducer. In Proceedings of the IEEE Ultrasonics Symposium (Vol. 2, pp. 1443-1446). IEEE.

Experimental studies of using of split beam transducer for prostate cancer therapy in comparison to single beam transducer. / Wu, Jimmy S J; Sanghvi, Narendra T.; Phillips, Michael H.; Kuznetsov, M.; Foster, Richard; Bihrle, Richard; Gardner, Thomas; Umemura, S. I.

Proceedings of the IEEE Ultrasonics Symposium. Vol. 2 IEEE, 1999. p. 1443-1446.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Wu, JSJ, Sanghvi, NT, Phillips, MH, Kuznetsov, M, Foster, R, Bihrle, R, Gardner, T & Umemura, SI 1999, Experimental studies of using of split beam transducer for prostate cancer therapy in comparison to single beam transducer. in Proceedings of the IEEE Ultrasonics Symposium. vol. 2, IEEE, pp. 1443-1446, 1999 IEEE Ultrasonics Symposium, Caesars Tahoe, NV, USA, 10/17/99.
Wu JSJ, Sanghvi NT, Phillips MH, Kuznetsov M, Foster R, Bihrle R et al. Experimental studies of using of split beam transducer for prostate cancer therapy in comparison to single beam transducer. In Proceedings of the IEEE Ultrasonics Symposium. Vol. 2. IEEE. 1999. p. 1443-1446
Wu, Jimmy S J ; Sanghvi, Narendra T. ; Phillips, Michael H. ; Kuznetsov, M. ; Foster, Richard ; Bihrle, Richard ; Gardner, Thomas ; Umemura, S. I. / Experimental studies of using of split beam transducer for prostate cancer therapy in comparison to single beam transducer. Proceedings of the IEEE Ultrasonics Symposium. Vol. 2 IEEE, 1999. pp. 1443-1446
@inproceedings{5dacd5f756684aa0ad4a88bbce047b85,
title = "Experimental studies of using of split beam transducer for prostate cancer therapy in comparison to single beam transducer",
abstract = "A 'split beam' transducer arrangement was adapted for the existing benign prostatic hyperplasia (BPH) high intensity focused ultrasound (HIFU) treatment device, Sonablate - 200 (manufactured by Focus Surgery Inc., Indianapolis, IN) for the treatment of localized prostate cancer. In the split beam configuration the HIFU beam is divided into several beams to create a larger treatment volume per ultrasound exposure which can reduce the overall treatment time. The objective of current study was to compare the necrosis volume and temperature patterns produced from 'single beam' and 'split beam' operating configurations. Experiments were performed on different test objects including Mylar strip, plexiglass, turkey breast tissue (in-vitro) and in vivo dog prostates. The results showed that the split beam configuration created larger lesion volume for the same exposure time while keeping the temperature near the rectal wall at the safe levels. Thus split beam transducer (SBT) configuration should be effective and efficient in clinical application for the prostate cancer treatment.",
author = "Wu, {Jimmy S J} and Sanghvi, {Narendra T.} and Phillips, {Michael H.} and M. Kuznetsov and Richard Foster and Richard Bihrle and Thomas Gardner and Umemura, {S. I.}",
year = "1999",
language = "English (US)",
volume = "2",
pages = "1443--1446",
booktitle = "Proceedings of the IEEE Ultrasonics Symposium",
publisher = "IEEE",

}

TY - GEN

T1 - Experimental studies of using of split beam transducer for prostate cancer therapy in comparison to single beam transducer

AU - Wu, Jimmy S J

AU - Sanghvi, Narendra T.

AU - Phillips, Michael H.

AU - Kuznetsov, M.

AU - Foster, Richard

AU - Bihrle, Richard

AU - Gardner, Thomas

AU - Umemura, S. I.

PY - 1999

Y1 - 1999

N2 - A 'split beam' transducer arrangement was adapted for the existing benign prostatic hyperplasia (BPH) high intensity focused ultrasound (HIFU) treatment device, Sonablate - 200 (manufactured by Focus Surgery Inc., Indianapolis, IN) for the treatment of localized prostate cancer. In the split beam configuration the HIFU beam is divided into several beams to create a larger treatment volume per ultrasound exposure which can reduce the overall treatment time. The objective of current study was to compare the necrosis volume and temperature patterns produced from 'single beam' and 'split beam' operating configurations. Experiments were performed on different test objects including Mylar strip, plexiglass, turkey breast tissue (in-vitro) and in vivo dog prostates. The results showed that the split beam configuration created larger lesion volume for the same exposure time while keeping the temperature near the rectal wall at the safe levels. Thus split beam transducer (SBT) configuration should be effective and efficient in clinical application for the prostate cancer treatment.

AB - A 'split beam' transducer arrangement was adapted for the existing benign prostatic hyperplasia (BPH) high intensity focused ultrasound (HIFU) treatment device, Sonablate - 200 (manufactured by Focus Surgery Inc., Indianapolis, IN) for the treatment of localized prostate cancer. In the split beam configuration the HIFU beam is divided into several beams to create a larger treatment volume per ultrasound exposure which can reduce the overall treatment time. The objective of current study was to compare the necrosis volume and temperature patterns produced from 'single beam' and 'split beam' operating configurations. Experiments were performed on different test objects including Mylar strip, plexiglass, turkey breast tissue (in-vitro) and in vivo dog prostates. The results showed that the split beam configuration created larger lesion volume for the same exposure time while keeping the temperature near the rectal wall at the safe levels. Thus split beam transducer (SBT) configuration should be effective and efficient in clinical application for the prostate cancer treatment.

UR - http://www.scopus.com/inward/record.url?scp=0033296584&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0033296584&partnerID=8YFLogxK

M3 - Conference contribution

AN - SCOPUS:0033296584

VL - 2

SP - 1443

EP - 1446

BT - Proceedings of the IEEE Ultrasonics Symposium

PB - IEEE

ER -