Exploration of environmental and genetic risk factors for Alzheimer's disease: The value of cross-cultural studies

Research output: Contribution to journalArticle

15 Scopus citations

Abstract

Advances in molecular genetics have revolutionized epidemiological research. It is now possible to combine the techniques of population genetics with research on risk factors to construct genetic-environmental interactive models that explain geographic-ethnic variations in disease rates. Cross-cultural studies involving populations from developing and developed countries offer a unique opportunity for constructing these models by providing a wide diversity of environmental exposures. Results from a comparative Indianapolis-Ibadan study suggest that Alzheimer's disease incidence rates are lower in Yoruba than in African Americans and that these lower rates may be due to a combination of genetic and environmental, primarily dietary, influences.

Original languageEnglish (US)
Pages (from-to)98-101
Number of pages4
JournalCurrent Directions in Psychological Science
Volume10
Issue number3
DOIs
StatePublished - Jun 2001

Keywords

  • Alzheimer's disease
  • Cross-cultural
  • Genetics

ASJC Scopus subject areas

  • Psychology(all)

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