Expression of hydra head activator in newt tissues and effects on limb regeneration

E. J. Fuentes, Anthony Mescher, R. Ekman, P. A. Tsonis

Research output: Contribution to journalArticle

Abstract

In this study, the presence of the hydra head activator (HHA) neuropeptide and its influence on regenerating newt limbs (Notophthalmus viridescens) was investigated. Immunohistological analysis has localized the HHA neuropeptide in the adult newt brain, eye, intestine, and regenerating blastema. Experiments in which 9 day limb regenerates were denervated and subsequently implanted with HHA-soaked beads suggest a slight progression of blastema growth compared to denervated controls.

Original languageEnglish (US)
Pages (from-to)59-63
Number of pages5
JournalIn Vivo
Volume7
Issue number1
StatePublished - 1993
Externally publishedYes

Fingerprint

Hydra
Salamandridae
Neuropeptides
Regeneration
Extremities
Head
Tissue
Notophthalmus viridescens
Brain
Intestines
Experiments
Growth

Keywords

  • hydra head activator
  • limb generation
  • newt

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Expression of hydra head activator in newt tissues and effects on limb regeneration. / Fuentes, E. J.; Mescher, Anthony; Ekman, R.; Tsonis, P. A.

In: In Vivo, Vol. 7, No. 1, 1993, p. 59-63.

Research output: Contribution to journalArticle

Fuentes, EJ, Mescher, A, Ekman, R & Tsonis, PA 1993, 'Expression of hydra head activator in newt tissues and effects on limb regeneration', In Vivo, vol. 7, no. 1, pp. 59-63.
Fuentes, E. J. ; Mescher, Anthony ; Ekman, R. ; Tsonis, P. A. / Expression of hydra head activator in newt tissues and effects on limb regeneration. In: In Vivo. 1993 ; Vol. 7, No. 1. pp. 59-63.
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