Expression of pituitary hormone mRNAS in the Xenopus oocyte

C. Yan, N. Ben-Jonathan

Research output: Contribution to journalArticle

Abstract

The Xenopus L. oocyte is capable of expressing foreign proteins and correctly carrying out post-translational modification. It is also capable of directing proteins into the correct intracellular and cytoplasmic compartments. Many foreign proteins synthesized in oocytes acquire native activity. To apply the Xenopus oocyte expression system in studying neuroendocrine peptides, we successfully expressed pituitary hormones in the Xenopus oocyte by microinjection. This provides an useful tool for studying their biological function and production.

Original languageEnglish (US)
Pages (from-to)215-220
Number of pages6
JournalNeuroendocrinology Letters
Volume16
Issue number4
StatePublished - Jan 1 1994
Externally publishedYes

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology
  • Neurology
  • Endocrine and Autonomic Systems
  • Clinical Neurology
  • Psychiatry and Mental health

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