Exstrophy polyp is a unique pathology entity

Rong Fan, David J. Grignon, Audrey Rhee, Kristen K. Meldrum, Liang Cheng

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

Classic bladder exstrophy is a rare congenital malformation occurring with an incidence of about 1 in 50 000 live births. Polypoid lesions frequently arise in the exstrophic bladder template; this has been well described in the pediatric urological literature. These lesions, however, are not as familiar to pathologists and oftentimes constitute diagnostic challenges. Careful observation revealed that these polyps are unique in their histopathologic appearance, with deep penetrating nests of urothelium or cysts and surrounding concentric fibrosis. Combining the unique clinical setting, a separate pathologic and diagnostic entity should be initiated for this type of polyp; we propose the term 'bladder exstrophy polyp' or simply an 'exstrophy polyp.'

Original languageEnglish (US)
Pages (from-to)471-477
Number of pages7
JournalPediatric and Developmental Pathology
Volume15
Issue number6
DOIs
StatePublished - Nov 1 2012

Keywords

  • Bladder hemangioma
  • Exstrophy bladder
  • Fibroepithelial polyp
  • Inflammatory polyp
  • Pathology
  • Polypoid cystitis
  • Polyps

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Pathology and Forensic Medicine

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