Exstrophy polyp is a unique pathology entity

Rong Fan, David Grignon, Audrey Rhee, Kristen K. Meldrum, Liang Cheng

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Classic bladder exstrophy is a rare congenital malformation occurring with an incidence of about 1 in 50 000 live births. Polypoid lesions frequently arise in the exstrophic bladder template; this has been well described in the pediatric urological literature. These lesions, however, are not as familiar to pathologists and oftentimes constitute diagnostic challenges. Careful observation revealed that these polyps are unique in their histopathologic appearance, with deep penetrating nests of urothelium or cysts and surrounding concentric fibrosis. Combining the unique clinical setting, a separate pathologic and diagnostic entity should be initiated for this type of polyp; we propose the term 'bladder exstrophy polyp' or simply an 'exstrophy polyp.'

Original languageEnglish
Pages (from-to)471-477
Number of pages7
JournalPediatric and Developmental Pathology
Volume15
Issue number6
DOIs
StatePublished - Nov 2012

Fingerprint

Polyps
Bladder Exstrophy
Pathology
Urothelium
Live Birth
Cysts
Urinary Bladder
Fibrosis
Observation
Pediatrics
Incidence

Keywords

  • Bladder hemangioma
  • Exstrophy bladder
  • Fibroepithelial polyp
  • Inflammatory polyp
  • Pathology
  • Polypoid cystitis
  • Polyps

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Pathology and Forensic Medicine

Cite this

Exstrophy polyp is a unique pathology entity. / Fan, Rong; Grignon, David; Rhee, Audrey; Meldrum, Kristen K.; Cheng, Liang.

In: Pediatric and Developmental Pathology, Vol. 15, No. 6, 11.2012, p. 471-477.

Research output: Contribution to journalArticle

Fan, Rong ; Grignon, David ; Rhee, Audrey ; Meldrum, Kristen K. ; Cheng, Liang. / Exstrophy polyp is a unique pathology entity. In: Pediatric and Developmental Pathology. 2012 ; Vol. 15, No. 6. pp. 471-477.
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