Extraction of drug-drug interactions using all paths graph kernel

Shreyas Karnik, Abhinita Subhadarshini, Zhiping Wang, Luis M. Rocha, Lang Li

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)

Abstract

Drug-drug interactions (DDIs) cause nearly 3% of all hospital admissions. Regulatory authorities such as the Food and Drug Administration (FDA) and the pharmaceutical companies keep a rigorous tab on the DDIs. The major source of DDI information is the biomedical literature. In this paper we present a DDI extraction approach based on all paths graph kernel [1] from the DrugDDI corpus [2]. We also evaluate the method on an in-house developed clinical in vivo pharmacokinetic DDI corpus. When the DDI extraction model was evaluated on the test dataset from both corpora we recorded a F-score of 0.658 on the clinical in vivo pharmacokinetic DDI corpus and 0.16 on the DrugDDI corpus.

Original languageEnglish
Title of host publicationCEUR Workshop Proceedings
Pages83-88
Number of pages6
Volume761
StatePublished - 2011
Event1st Challenge Task on Drug-Drug Interaction Extraction 2011, DDIExtraction 2011 - Co-located with the 27th Conference of the Spanish Society for Natural Language Processing, SEPLN 2011 - Huelva, Spain
Duration: Sep 7 2011Sep 7 2011

Other

Other1st Challenge Task on Drug-Drug Interaction Extraction 2011, DDIExtraction 2011 - Co-located with the 27th Conference of the Spanish Society for Natural Language Processing, SEPLN 2011
CountrySpain
CityHuelva
Period9/7/119/7/11

Fingerprint

Drug interactions
Pharmacokinetics
Drug products

ASJC Scopus subject areas

  • Computer Science(all)

Cite this

Karnik, S., Subhadarshini, A., Wang, Z., Rocha, L. M., & Li, L. (2011). Extraction of drug-drug interactions using all paths graph kernel. In CEUR Workshop Proceedings (Vol. 761, pp. 83-88)

Extraction of drug-drug interactions using all paths graph kernel. / Karnik, Shreyas; Subhadarshini, Abhinita; Wang, Zhiping; Rocha, Luis M.; Li, Lang.

CEUR Workshop Proceedings. Vol. 761 2011. p. 83-88.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Karnik, S, Subhadarshini, A, Wang, Z, Rocha, LM & Li, L 2011, Extraction of drug-drug interactions using all paths graph kernel. in CEUR Workshop Proceedings. vol. 761, pp. 83-88, 1st Challenge Task on Drug-Drug Interaction Extraction 2011, DDIExtraction 2011 - Co-located with the 27th Conference of the Spanish Society for Natural Language Processing, SEPLN 2011, Huelva, Spain, 9/7/11.
Karnik S, Subhadarshini A, Wang Z, Rocha LM, Li L. Extraction of drug-drug interactions using all paths graph kernel. In CEUR Workshop Proceedings. Vol. 761. 2011. p. 83-88
Karnik, Shreyas ; Subhadarshini, Abhinita ; Wang, Zhiping ; Rocha, Luis M. ; Li, Lang. / Extraction of drug-drug interactions using all paths graph kernel. CEUR Workshop Proceedings. Vol. 761 2011. pp. 83-88
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