Factors associated with human papillomavirus (HPV) test acceptability in primary screening for cervical cancer: A mixed methods research synthesis

Ovidiu Tatar, Erika Thompson, Anila Naz, Samara Perez, Gilla K. Shapiro, Kristina Wade, Gregory Zimet, Vladimir Gilca, Monika Janda, Jessica Kahn, Ellen Daley, Zeev Rosberger

Research output: Contribution to journalReview article

1 Citation (Scopus)

Abstract

Primary screening for cervical cancer is transitioning from the longstanding Pap smear towards implementation of an HPV-DNA test, which is more sensitive than Pap cytology in detecting high-risk lesions and offers greater protection against invasive cervical carcinomas. Based on these results, many countries are recommending and implementing HPV testing-based screening programs. Understanding what factors (e.g., knowledge, attitudes) will impact on HPV test acceptability by women is crucial for ensuring adequate public health practices to optimize cervical screening uptake. We used mixed methods research synthesis to provide a categorization of the relevant factors related to HPV primary screening for cervical cancer and describe their influence on women's acceptability of HPV testing. We searched Medline, Embase, PsycINFO, CINAHL, Global Health and Web of Science for journal articles between January 1, 1980 and October 31, 2017 and retained 22 empirical articles. Our results show that while most factors associated with HPV test acceptability are included in the Health Belief Model and/or Theory of Planned Behavior (e.g., attitudes, knowledge), other important factors are not encompassed by these theoretical frameworks (e.g., health behaviors, negative emotional reactions related to HPV testing). The direction of influence of psychosocial factors on HPV test acceptability was synthesized based on 14 quantitative studies as: facilitators (e.g., high perceived HPV test benefits), barriers (e.g., negative attitudes towards increased screening intervals), contradictory evidence (e.g., sexual history) and no impact (e.g., high perceived severity of HPV infection). Further population-based studies are needed to confirm the impact of these factors on HPV-based screening acceptability.

Original languageEnglish (US)
Pages (from-to)40-50
Number of pages11
JournalPreventive Medicine
Volume116
DOIs
StatePublished - Nov 1 2018

Fingerprint

Uterine Cervical Neoplasms
Research
Human Papillomavirus DNA Tests
Public Health Practice
Papanicolaou Test
Papillomavirus Infections
Health Behavior
Cell Biology
Psychology
Carcinoma
Health

Keywords

  • Barriers
  • Facilitators
  • Human papillomavirus
  • Human Papillomavirus DNA Tests
  • Mass Screening
  • Mixed methods
  • Psychology
  • Psychosocial
  • Review
  • Uterine Cervical Neoplasms

ASJC Scopus subject areas

  • Epidemiology
  • Public Health, Environmental and Occupational Health

Cite this

Factors associated with human papillomavirus (HPV) test acceptability in primary screening for cervical cancer : A mixed methods research synthesis. / Tatar, Ovidiu; Thompson, Erika; Naz, Anila; Perez, Samara; Shapiro, Gilla K.; Wade, Kristina; Zimet, Gregory; Gilca, Vladimir; Janda, Monika; Kahn, Jessica; Daley, Ellen; Rosberger, Zeev.

In: Preventive Medicine, Vol. 116, 01.11.2018, p. 40-50.

Research output: Contribution to journalReview article

Tatar, O, Thompson, E, Naz, A, Perez, S, Shapiro, GK, Wade, K, Zimet, G, Gilca, V, Janda, M, Kahn, J, Daley, E & Rosberger, Z 2018, 'Factors associated with human papillomavirus (HPV) test acceptability in primary screening for cervical cancer: A mixed methods research synthesis', Preventive Medicine, vol. 116, pp. 40-50. https://doi.org/10.1016/j.ypmed.2018.08.034
Tatar, Ovidiu ; Thompson, Erika ; Naz, Anila ; Perez, Samara ; Shapiro, Gilla K. ; Wade, Kristina ; Zimet, Gregory ; Gilca, Vladimir ; Janda, Monika ; Kahn, Jessica ; Daley, Ellen ; Rosberger, Zeev. / Factors associated with human papillomavirus (HPV) test acceptability in primary screening for cervical cancer : A mixed methods research synthesis. In: Preventive Medicine. 2018 ; Vol. 116. pp. 40-50.
@article{5063ff24b01948f5852425d12aa67553,
title = "Factors associated with human papillomavirus (HPV) test acceptability in primary screening for cervical cancer: A mixed methods research synthesis",
abstract = "Primary screening for cervical cancer is transitioning from the longstanding Pap smear towards implementation of an HPV-DNA test, which is more sensitive than Pap cytology in detecting high-risk lesions and offers greater protection against invasive cervical carcinomas. Based on these results, many countries are recommending and implementing HPV testing-based screening programs. Understanding what factors (e.g., knowledge, attitudes) will impact on HPV test acceptability by women is crucial for ensuring adequate public health practices to optimize cervical screening uptake. We used mixed methods research synthesis to provide a categorization of the relevant factors related to HPV primary screening for cervical cancer and describe their influence on women's acceptability of HPV testing. We searched Medline, Embase, PsycINFO, CINAHL, Global Health and Web of Science for journal articles between January 1, 1980 and October 31, 2017 and retained 22 empirical articles. Our results show that while most factors associated with HPV test acceptability are included in the Health Belief Model and/or Theory of Planned Behavior (e.g., attitudes, knowledge), other important factors are not encompassed by these theoretical frameworks (e.g., health behaviors, negative emotional reactions related to HPV testing). The direction of influence of psychosocial factors on HPV test acceptability was synthesized based on 14 quantitative studies as: facilitators (e.g., high perceived HPV test benefits), barriers (e.g., negative attitudes towards increased screening intervals), contradictory evidence (e.g., sexual history) and no impact (e.g., high perceived severity of HPV infection). Further population-based studies are needed to confirm the impact of these factors on HPV-based screening acceptability.",
keywords = "Barriers, Facilitators, Human papillomavirus, Human Papillomavirus DNA Tests, Mass Screening, Mixed methods, Psychology, Psychosocial, Review, Uterine Cervical Neoplasms",
author = "Ovidiu Tatar and Erika Thompson and Anila Naz and Samara Perez and Shapiro, {Gilla K.} and Kristina Wade and Gregory Zimet and Vladimir Gilca and Monika Janda and Jessica Kahn and Ellen Daley and Zeev Rosberger",
year = "2018",
month = "11",
day = "1",
doi = "10.1016/j.ypmed.2018.08.034",
language = "English (US)",
volume = "116",
pages = "40--50",
journal = "Preventive Medicine",
issn = "0091-7435",
publisher = "Academic Press Inc.",

}

TY - JOUR

T1 - Factors associated with human papillomavirus (HPV) test acceptability in primary screening for cervical cancer

T2 - A mixed methods research synthesis

AU - Tatar, Ovidiu

AU - Thompson, Erika

AU - Naz, Anila

AU - Perez, Samara

AU - Shapiro, Gilla K.

AU - Wade, Kristina

AU - Zimet, Gregory

AU - Gilca, Vladimir

AU - Janda, Monika

AU - Kahn, Jessica

AU - Daley, Ellen

AU - Rosberger, Zeev

PY - 2018/11/1

Y1 - 2018/11/1

N2 - Primary screening for cervical cancer is transitioning from the longstanding Pap smear towards implementation of an HPV-DNA test, which is more sensitive than Pap cytology in detecting high-risk lesions and offers greater protection against invasive cervical carcinomas. Based on these results, many countries are recommending and implementing HPV testing-based screening programs. Understanding what factors (e.g., knowledge, attitudes) will impact on HPV test acceptability by women is crucial for ensuring adequate public health practices to optimize cervical screening uptake. We used mixed methods research synthesis to provide a categorization of the relevant factors related to HPV primary screening for cervical cancer and describe their influence on women's acceptability of HPV testing. We searched Medline, Embase, PsycINFO, CINAHL, Global Health and Web of Science for journal articles between January 1, 1980 and October 31, 2017 and retained 22 empirical articles. Our results show that while most factors associated with HPV test acceptability are included in the Health Belief Model and/or Theory of Planned Behavior (e.g., attitudes, knowledge), other important factors are not encompassed by these theoretical frameworks (e.g., health behaviors, negative emotional reactions related to HPV testing). The direction of influence of psychosocial factors on HPV test acceptability was synthesized based on 14 quantitative studies as: facilitators (e.g., high perceived HPV test benefits), barriers (e.g., negative attitudes towards increased screening intervals), contradictory evidence (e.g., sexual history) and no impact (e.g., high perceived severity of HPV infection). Further population-based studies are needed to confirm the impact of these factors on HPV-based screening acceptability.

AB - Primary screening for cervical cancer is transitioning from the longstanding Pap smear towards implementation of an HPV-DNA test, which is more sensitive than Pap cytology in detecting high-risk lesions and offers greater protection against invasive cervical carcinomas. Based on these results, many countries are recommending and implementing HPV testing-based screening programs. Understanding what factors (e.g., knowledge, attitudes) will impact on HPV test acceptability by women is crucial for ensuring adequate public health practices to optimize cervical screening uptake. We used mixed methods research synthesis to provide a categorization of the relevant factors related to HPV primary screening for cervical cancer and describe their influence on women's acceptability of HPV testing. We searched Medline, Embase, PsycINFO, CINAHL, Global Health and Web of Science for journal articles between January 1, 1980 and October 31, 2017 and retained 22 empirical articles. Our results show that while most factors associated with HPV test acceptability are included in the Health Belief Model and/or Theory of Planned Behavior (e.g., attitudes, knowledge), other important factors are not encompassed by these theoretical frameworks (e.g., health behaviors, negative emotional reactions related to HPV testing). The direction of influence of psychosocial factors on HPV test acceptability was synthesized based on 14 quantitative studies as: facilitators (e.g., high perceived HPV test benefits), barriers (e.g., negative attitudes towards increased screening intervals), contradictory evidence (e.g., sexual history) and no impact (e.g., high perceived severity of HPV infection). Further population-based studies are needed to confirm the impact of these factors on HPV-based screening acceptability.

KW - Barriers

KW - Facilitators

KW - Human papillomavirus

KW - Human Papillomavirus DNA Tests

KW - Mass Screening

KW - Mixed methods

KW - Psychology

KW - Psychosocial

KW - Review

KW - Uterine Cervical Neoplasms

UR - http://www.scopus.com/inward/record.url?scp=85052727233&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85052727233&partnerID=8YFLogxK

U2 - 10.1016/j.ypmed.2018.08.034

DO - 10.1016/j.ypmed.2018.08.034

M3 - Review article

C2 - 30172799

AN - SCOPUS:85052727233

VL - 116

SP - 40

EP - 50

JO - Preventive Medicine

JF - Preventive Medicine

SN - 0091-7435

ER -