Factors sustaining pediatric adherence to antiretroviral therapy in Western Kenya

Rachel Vreeman, Winstone M. Nyandiko, Samwel O. Ayaya, Eunice G. Walumbe, David Marrero, Thomas Inui

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abstract

Antiretroviral therapy (ART) requires nearly perfect adherence to be effective. Although 90% of HIV-infected children live in Africa, there are limited data on pediatric adherence from this multicultural continent.We conducted a qualitative study to identify key factors contributing to pediatric ART adherence. Ten focus group discussions (N = 85) and 35 individual interviews were conducted with parents and guardians of HIV-infected children receiving ART in western Kenya. Interviews covered multiple aspects of the experience of having children take ART and factors that inhibited or facilitated medication adherence. Constant comparison, progressive coding, and triangulation methods were used to arrive at a culturally contextualized, conceptual model for pediatric ART adherence derived from the descriptions of the lived experience in this resource-limited setting. Child care, including sustained ART adherence, depends on interacting cultural and environmental determinants at the levels of the individual child, parent/caregiver, household, community, health care system, and society.

Original languageEnglish
Pages (from-to)1716-1729
Number of pages14
JournalQualitative Health Research
Volume19
Issue number12
DOIs
StatePublished - Dec 2009

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Kenya
Pediatrics
Therapeutics
Community Health Planning
HIV
Interviews
Community Health Services
Medication Adherence
Child Care
Focus Groups
Caregivers
Parents
Delivery of Health Care

Keywords

  • Adherence
  • Africa
  • Grounded theory
  • HIV/AIDS
  • Pediatrics
  • Stigma

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

Cite this

Factors sustaining pediatric adherence to antiretroviral therapy in Western Kenya. / Vreeman, Rachel; Nyandiko, Winstone M.; Ayaya, Samwel O.; Walumbe, Eunice G.; Marrero, David; Inui, Thomas.

In: Qualitative Health Research, Vol. 19, No. 12, 12.2009, p. 1716-1729.

Research output: Contribution to journalArticle

Vreeman, Rachel ; Nyandiko, Winstone M. ; Ayaya, Samwel O. ; Walumbe, Eunice G. ; Marrero, David ; Inui, Thomas. / Factors sustaining pediatric adherence to antiretroviral therapy in Western Kenya. In: Qualitative Health Research. 2009 ; Vol. 19, No. 12. pp. 1716-1729.
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