Familial amyloidotic polyneuropathy

Merrill Benson, Richard L. Roudebush

Research output: Contribution to journalArticle

100 Citations (Scopus)

Abstract

Amyloidosis has received considerable attention recently because of its association with Alzheimer's disease. Actually, the amyloid in the cortical plaques, which is characteristic of Alzheimer's disease, is a localized form of amyloid deposition. Although intracranial vascular amyloid deposits which contain the A4 or β-protein are usually associated with Alzheimer's disease, deposition of this amyloid fibril substance in other organs of the body has not been described1. Much less attention has been paid to amyloid involvement of the PNS which is a fascinating subject in itself and is the subject of this review.

Original languageEnglish (US)
Pages (from-to)88-92
Number of pages5
JournalTrends in Neurosciences
Volume12
Issue number3
DOIs
StatePublished - 1989
Externally publishedYes

Fingerprint

Polyneuropathies
Amyloid
Alzheimer Disease
Amyloid Plaques
Amyloidosis
Blood Vessels
Proteins

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Familial amyloidotic polyneuropathy. / Benson, Merrill; Roudebush, Richard L.

In: Trends in Neurosciences, Vol. 12, No. 3, 1989, p. 88-92.

Research output: Contribution to journalArticle

Benson, Merrill ; Roudebush, Richard L. / Familial amyloidotic polyneuropathy. In: Trends in Neurosciences. 1989 ; Vol. 12, No. 3. pp. 88-92.
@article{6b5901e789294a629ef4fa6bdc2f20d5,
title = "Familial amyloidotic polyneuropathy",
abstract = "Amyloidosis has received considerable attention recently because of its association with Alzheimer's disease. Actually, the amyloid in the cortical plaques, which is characteristic of Alzheimer's disease, is a localized form of amyloid deposition. Although intracranial vascular amyloid deposits which contain the A4 or β-protein are usually associated with Alzheimer's disease, deposition of this amyloid fibril substance in other organs of the body has not been described1. Much less attention has been paid to amyloid involvement of the PNS which is a fascinating subject in itself and is the subject of this review.",
author = "Merrill Benson and Roudebush, {Richard L.}",
year = "1989",
doi = "10.1016/0166-2236(89)90162-8",
language = "English (US)",
volume = "12",
pages = "88--92",
journal = "Trends in Neurosciences",
issn = "0378-5912",
publisher = "Elsevier Limited",
number = "3",

}

TY - JOUR

T1 - Familial amyloidotic polyneuropathy

AU - Benson, Merrill

AU - Roudebush, Richard L.

PY - 1989

Y1 - 1989

N2 - Amyloidosis has received considerable attention recently because of its association with Alzheimer's disease. Actually, the amyloid in the cortical plaques, which is characteristic of Alzheimer's disease, is a localized form of amyloid deposition. Although intracranial vascular amyloid deposits which contain the A4 or β-protein are usually associated with Alzheimer's disease, deposition of this amyloid fibril substance in other organs of the body has not been described1. Much less attention has been paid to amyloid involvement of the PNS which is a fascinating subject in itself and is the subject of this review.

AB - Amyloidosis has received considerable attention recently because of its association with Alzheimer's disease. Actually, the amyloid in the cortical plaques, which is characteristic of Alzheimer's disease, is a localized form of amyloid deposition. Although intracranial vascular amyloid deposits which contain the A4 or β-protein are usually associated with Alzheimer's disease, deposition of this amyloid fibril substance in other organs of the body has not been described1. Much less attention has been paid to amyloid involvement of the PNS which is a fascinating subject in itself and is the subject of this review.

UR - http://www.scopus.com/inward/record.url?scp=0024503518&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0024503518&partnerID=8YFLogxK

U2 - 10.1016/0166-2236(89)90162-8

DO - 10.1016/0166-2236(89)90162-8

M3 - Article

VL - 12

SP - 88

EP - 92

JO - Trends in Neurosciences

JF - Trends in Neurosciences

SN - 0378-5912

IS - 3

ER -