Familial cerebral amyloid angiopathy related to stroke and dementia

B. Frangione, T. Révész, Ruben Vidal, J. Holton, T. Lashley, H. Houlden, N. Wood, A. Rostagno, G. Plant, J. Ghiso

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

The term cerebral amyloid angiopathy (CAA) refers to the specific deposition of amyloid fibrils in the walls of leptomeningeal and cortical arteries, arterioles and, although less frequently, in capillaries and veins. It is commonly associated with Alzheimer's disease. Down syndrome and normal aging, as well as with a variety of familial conditions related to stroke and/or dementia: hereditary cerebral hemorrhage with amyloidosis of Icelandic type (HCHWA-I), various inherited disorders linked to Aβ mutants (including the Dutch variant of HCHWA), and the recently described chromosome 13 familial dementia in British and Danish kindreds. This review focuses on four different types of hereditary CAA, emphasizing the notion that CAA is not only related to stroke but also to neurodegeneration and dementia of the Alzheimer's type.

Original languageEnglish (US)
Pages (from-to)36-42
Number of pages7
JournalAmyloid
Volume8
Issue numberSUPPL. 1
StatePublished - 2001
Externally publishedYes

Fingerprint

Familial Cerebral Amyloid Angiopathy
Cerebral Amyloid Angiopathy
Dementia
Stroke
Alzheimer Disease
Chromosomes, Human, Pair 13
Arterioles
Down Syndrome
Amyloid
Veins
Arteries

Keywords

  • Amyloid angiopathy
  • Cerebra
  • Dementia
  • Familial
  • Stroke

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Medicine(all)

Cite this

Frangione, B., Révész, T., Vidal, R., Holton, J., Lashley, T., Houlden, H., ... Ghiso, J. (2001). Familial cerebral amyloid angiopathy related to stroke and dementia. Amyloid, 8(SUPPL. 1), 36-42.

Familial cerebral amyloid angiopathy related to stroke and dementia. / Frangione, B.; Révész, T.; Vidal, Ruben; Holton, J.; Lashley, T.; Houlden, H.; Wood, N.; Rostagno, A.; Plant, G.; Ghiso, J.

In: Amyloid, Vol. 8, No. SUPPL. 1, 2001, p. 36-42.

Research output: Contribution to journalArticle

Frangione, B, Révész, T, Vidal, R, Holton, J, Lashley, T, Houlden, H, Wood, N, Rostagno, A, Plant, G & Ghiso, J 2001, 'Familial cerebral amyloid angiopathy related to stroke and dementia', Amyloid, vol. 8, no. SUPPL. 1, pp. 36-42.
Frangione B, Révész T, Vidal R, Holton J, Lashley T, Houlden H et al. Familial cerebral amyloid angiopathy related to stroke and dementia. Amyloid. 2001;8(SUPPL. 1):36-42.
Frangione, B. ; Révész, T. ; Vidal, Ruben ; Holton, J. ; Lashley, T. ; Houlden, H. ; Wood, N. ; Rostagno, A. ; Plant, G. ; Ghiso, J. / Familial cerebral amyloid angiopathy related to stroke and dementia. In: Amyloid. 2001 ; Vol. 8, No. SUPPL. 1. pp. 36-42.
@article{e3ad82483d794dd28ab5420649c597eb,
title = "Familial cerebral amyloid angiopathy related to stroke and dementia",
abstract = "The term cerebral amyloid angiopathy (CAA) refers to the specific deposition of amyloid fibrils in the walls of leptomeningeal and cortical arteries, arterioles and, although less frequently, in capillaries and veins. It is commonly associated with Alzheimer's disease. Down syndrome and normal aging, as well as with a variety of familial conditions related to stroke and/or dementia: hereditary cerebral hemorrhage with amyloidosis of Icelandic type (HCHWA-I), various inherited disorders linked to Aβ mutants (including the Dutch variant of HCHWA), and the recently described chromosome 13 familial dementia in British and Danish kindreds. This review focuses on four different types of hereditary CAA, emphasizing the notion that CAA is not only related to stroke but also to neurodegeneration and dementia of the Alzheimer's type.",
keywords = "Amyloid angiopathy, Cerebra, Dementia, Familial, Stroke",
author = "B. Frangione and T. R{\'e}v{\'e}sz and Ruben Vidal and J. Holton and T. Lashley and H. Houlden and N. Wood and A. Rostagno and G. Plant and J. Ghiso",
year = "2001",
language = "English (US)",
volume = "8",
pages = "36--42",
journal = "Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis",
issn = "1350-6129",
publisher = "Informa Healthcare",
number = "SUPPL. 1",

}

TY - JOUR

T1 - Familial cerebral amyloid angiopathy related to stroke and dementia

AU - Frangione, B.

AU - Révész, T.

AU - Vidal, Ruben

AU - Holton, J.

AU - Lashley, T.

AU - Houlden, H.

AU - Wood, N.

AU - Rostagno, A.

AU - Plant, G.

AU - Ghiso, J.

PY - 2001

Y1 - 2001

N2 - The term cerebral amyloid angiopathy (CAA) refers to the specific deposition of amyloid fibrils in the walls of leptomeningeal and cortical arteries, arterioles and, although less frequently, in capillaries and veins. It is commonly associated with Alzheimer's disease. Down syndrome and normal aging, as well as with a variety of familial conditions related to stroke and/or dementia: hereditary cerebral hemorrhage with amyloidosis of Icelandic type (HCHWA-I), various inherited disorders linked to Aβ mutants (including the Dutch variant of HCHWA), and the recently described chromosome 13 familial dementia in British and Danish kindreds. This review focuses on four different types of hereditary CAA, emphasizing the notion that CAA is not only related to stroke but also to neurodegeneration and dementia of the Alzheimer's type.

AB - The term cerebral amyloid angiopathy (CAA) refers to the specific deposition of amyloid fibrils in the walls of leptomeningeal and cortical arteries, arterioles and, although less frequently, in capillaries and veins. It is commonly associated with Alzheimer's disease. Down syndrome and normal aging, as well as with a variety of familial conditions related to stroke and/or dementia: hereditary cerebral hemorrhage with amyloidosis of Icelandic type (HCHWA-I), various inherited disorders linked to Aβ mutants (including the Dutch variant of HCHWA), and the recently described chromosome 13 familial dementia in British and Danish kindreds. This review focuses on four different types of hereditary CAA, emphasizing the notion that CAA is not only related to stroke but also to neurodegeneration and dementia of the Alzheimer's type.

KW - Amyloid angiopathy

KW - Cerebra

KW - Dementia

KW - Familial

KW - Stroke

UR - http://www.scopus.com/inward/record.url?scp=0034828250&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034828250&partnerID=8YFLogxK

M3 - Article

C2 - 11676288

AN - SCOPUS:0034828250

VL - 8

SP - 36

EP - 42

JO - Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis

JF - Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis

SN - 1350-6129

IS - SUPPL. 1

ER -