Familial gastroesophageal reflux and development of Barrett's esophagus

D. W. Crabb, M. A. Berk, T. R. Hall, P. M. Conneally, A. A. Biegel, G. A. Lehman

Research output: Contribution to journalArticle

87 Citations (Scopus)

Abstract

The family of an elderly man with Barrett's esophagus was examined for gastroesophageal reflux and development of Barrett's esophagus. All 5 living children have gastroesophageal reflux or esophagitis, or both, and 3 have unequivocal Barrett's esophagus. Two third-generation descendents have gastroesophageal reflux. This pattern suggests autosomal dominant transmission of the gastroesophageal reflux trait. The family also has a high prevalence of cancer, which may represent the cancer family syndrome.

Original languageEnglish
Pages (from-to)52-54
Number of pages3
JournalAnnals of Internal Medicine
Volume103
Issue number1
StatePublished - 1985

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Barrett Esophagus
Gastroesophageal Reflux
Peptic Esophagitis
Neoplasms

ASJC Scopus subject areas

  • Medicine(all)

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Crabb, D. W., Berk, M. A., Hall, T. R., Conneally, P. M., Biegel, A. A., & Lehman, G. A. (1985). Familial gastroesophageal reflux and development of Barrett's esophagus. Annals of Internal Medicine, 103(1), 52-54.

Familial gastroesophageal reflux and development of Barrett's esophagus. / Crabb, D. W.; Berk, M. A.; Hall, T. R.; Conneally, P. M.; Biegel, A. A.; Lehman, G. A.

In: Annals of Internal Medicine, Vol. 103, No. 1, 1985, p. 52-54.

Research output: Contribution to journalArticle

Crabb, DW, Berk, MA, Hall, TR, Conneally, PM, Biegel, AA & Lehman, GA 1985, 'Familial gastroesophageal reflux and development of Barrett's esophagus', Annals of Internal Medicine, vol. 103, no. 1, pp. 52-54.
Crabb, D. W. ; Berk, M. A. ; Hall, T. R. ; Conneally, P. M. ; Biegel, A. A. ; Lehman, G. A. / Familial gastroesophageal reflux and development of Barrett's esophagus. In: Annals of Internal Medicine. 1985 ; Vol. 103, No. 1. pp. 52-54.
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