Familial startle disease (hyperexplexia). Electrophysiologic studies

Research output: Contribution to journalArticle

39 Citations (Scopus)

Abstract

Six affected members from a family of 15 patients with familial startle disease (hyperexplexia) underwent extensive electrophysiologic evaluation. The most marked abnormality consisted of prominent C response 60 to 75 ms after median and peroneal nerve stimulation. The somatosensory evoked responses were also relatively high in amplitude. These findings suggest that hyperactive long-loop reflexes may constitute the physiologic basis of startle disease.

Original languageEnglish
Pages (from-to)71-74
Number of pages4
JournalArchives of Neurology
Volume41
Issue number1
StatePublished - 1984

Fingerprint

Peroneal Nerve
Median Nerve
Reflex
Hyperexplexia hereditary
Familial
Nerve
Stimulation
Evaluation

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Familial startle disease (hyperexplexia). Electrophysiologic studies. / Markand, Omkar; Garg, B. P.; Weaver, David.

In: Archives of Neurology, Vol. 41, No. 1, 1984, p. 71-74.

Research output: Contribution to journalArticle

@article{026756e06a9e43c1bed08c9b75d24e23,
title = "Familial startle disease (hyperexplexia). Electrophysiologic studies",
abstract = "Six affected members from a family of 15 patients with familial startle disease (hyperexplexia) underwent extensive electrophysiologic evaluation. The most marked abnormality consisted of prominent C response 60 to 75 ms after median and peroneal nerve stimulation. The somatosensory evoked responses were also relatively high in amplitude. These findings suggest that hyperactive long-loop reflexes may constitute the physiologic basis of startle disease.",
author = "Omkar Markand and Garg, {B. P.} and David Weaver",
year = "1984",
language = "English",
volume = "41",
pages = "71--74",
journal = "Archives of Neurology",
issn = "0003-9942",
publisher = "American Medical Association",
number = "1",

}

TY - JOUR

T1 - Familial startle disease (hyperexplexia). Electrophysiologic studies

AU - Markand, Omkar

AU - Garg, B. P.

AU - Weaver, David

PY - 1984

Y1 - 1984

N2 - Six affected members from a family of 15 patients with familial startle disease (hyperexplexia) underwent extensive electrophysiologic evaluation. The most marked abnormality consisted of prominent C response 60 to 75 ms after median and peroneal nerve stimulation. The somatosensory evoked responses were also relatively high in amplitude. These findings suggest that hyperactive long-loop reflexes may constitute the physiologic basis of startle disease.

AB - Six affected members from a family of 15 patients with familial startle disease (hyperexplexia) underwent extensive electrophysiologic evaluation. The most marked abnormality consisted of prominent C response 60 to 75 ms after median and peroneal nerve stimulation. The somatosensory evoked responses were also relatively high in amplitude. These findings suggest that hyperactive long-loop reflexes may constitute the physiologic basis of startle disease.

UR - http://www.scopus.com/inward/record.url?scp=0021357407&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0021357407&partnerID=8YFLogxK

M3 - Article

C2 - 6689893

AN - SCOPUS:0021357407

VL - 41

SP - 71

EP - 74

JO - Archives of Neurology

JF - Archives of Neurology

SN - 0003-9942

IS - 1

ER -