Fatal stongyloides hyperinfection in heart transplantation

Hicham Ziad El Masry, Jacqueline O'Donnell

Research output: Contribution to journalArticle

24 Scopus citations

Abstract

S stercoralis is an intestinal parasite that normally causes a chronic, low-grade, mostly asymptomatic infection. Hyperinfection syndrome and dissemination, with secondary sepsis, may occur in immunosuppressed patients, especially those on corticosteroid therapy. We present a case of fatal strongyloidiasis occurring in a patient 1 month after orthotopic heart transplantation (OHT). We assess the diagnostic challenges in these patients where pulmonary and gastrointestinal symptoms predominate as presenting clinical manifestations. We also investigate the role of screening and prophylactic anti-helmintic therapy in patients at high risk of harboring the occult intestinal infection.

Original languageEnglish (US)
Pages (from-to)1980-1983
Number of pages4
JournalJournal of Heart and Lung Transplantation
Volume24
Issue number11
DOIs
StatePublished - Nov 1 2005

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine
  • Transplantation

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