Ferritin stimulation of a monokine inhibitor of lipopolysaccharide- augmented myelopoiesis is ferroxidase dependent

R. Kreisberg, H. E. Broxmeyer, R. N. Moore

Research output: Contribution to journalComment/debate

2 Scopus citations

Abstract

Ferritin inhibition of myelopoiesis has been associated with intrinsic ferroxidase activity of heavy-chain ferritin and with production of a monokine inhibitor of lipopolysaccharide (LPS)-augmented monocytopoiesis. We report here that intrinsic ferroxidase activity of heavy-chain ferritin is required for stimulated production of the monokine inhibitor of LPS-augmented monocytopoiesis.

Original languageEnglish (US)
Pages (from-to)2991-2994
Number of pages4
JournalInfection and immunity
Volume62
Issue number7
StatePublished - 1994

ASJC Scopus subject areas

  • Parasitology
  • Microbiology
  • Immunology
  • Infectious Diseases

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