Fetal and neonatal rat intestinal capillaries

A TEM study of changes in the mural structure

A. J. Milici, Patrick Bankston

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

The development of intestinal mucosal capillaries was studied in Wistar rats from the fourteenth day of gestation through the second postnatal day with the transmission electron microscope. the microvessels develop first as continuous capillaries without a basal lamina and become fenestrated during later stages of gestation. In the thickened areas of the cytoplasm of endothelial cells at early stages, there is a paucity of pinocytotic vesicles; but some vesicles are observed which are larger than those in the adult. Later in gestation these larger vesicles can still be seen, but the frequency of their occurrence decreases with the maturation of the vessels. The intercellular junctions vary in length and shape, and the space between the outer leaflets of the apposed cell membranes is usually 20 nm. Surrounding the abluminal surface of the endothelium, the incipient basal lamina appears attenuated and incomplete until at least the second day of neonatal life.

Original languageEnglish
Pages (from-to)435-448
Number of pages14
JournalAmerican Journal of Anatomy
Volume160
Issue number4
StatePublished - 1981

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Basement Membrane
Pregnancy
Intercellular Junctions
Microvessels
Endothelium
Wistar Rats
Cytoplasm
Endothelial Cells
Cell Membrane
Electrons

ASJC Scopus subject areas

  • Anatomy

Cite this

Fetal and neonatal rat intestinal capillaries : A TEM study of changes in the mural structure. / Milici, A. J.; Bankston, Patrick.

In: American Journal of Anatomy, Vol. 160, No. 4, 1981, p. 435-448.

Research output: Contribution to journalArticle

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