Fine-needle aspiration cytology of cystic hypersecretory ductal carcinoma in situ of the breast: A case report

Shannon S. Kratzer, Harvey M. Cramer, Handel E. Reynolds, In Sook Seo, David F. Canal

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

Cystic hypersecretory intraductal carcinoma is an unusual, cystic form of intraductal breast carcinoma affecting middle-aged women. Cytopathologists have rarely encountered this lesion, with only 2 other cases having been previously reported (Colandrea et al., Arch Pathol Lab Med 1988;112:560-563; Kim et al., Acta Cytol 1997;41:892-896). In our case, the cytologic findings of both air-dried, Diff-Quik-stained and ethanol-fixed, Papanicolaou-stained smears are presented. The cytologic hallmarks of this entity include the presence of a few scattered epithelial cells with bland nuclear morphology in a background of extensive, amorphous, pink-staining material. Cytomorphologically, the differential diagnosis includes other entities containing pink-staining material such as colloid carcinoma, mucocele-like lesion of the breast, and benign fibrocystic change.

Original languageEnglish (US)
Pages (from-to)160-163
Number of pages4
JournalDiagnostic Cytopathology
Volume20
Issue number3
DOIs
StatePublished - Mar 1 1999

Keywords

  • Breast
  • Carcinoma
  • Fine-needle aspiration

ASJC Scopus subject areas

  • Anatomy

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