Five decades of urologic pathology: the accelerating expansion of knowledge in renal cell neoplasia

Gregory T. MacLennan, Liang Cheng

Research output: Contribution to journalArticle

Abstract

Those who are knowledgeable in cosmology inform us that the expansion of the universe is such that the velocity at which a distant galaxy is receding from the observer is continually increasing with time. We humbly paraphrase that as “The bigger the universe gets, the faster it gets bigger.” This is an interesting analogy for the expansion of knowledge in the field of renal tumor pathology over the past 30 to 50 years. It is clear that a multitude of dedicated investigators have devoted incalculable amounts of time and effort to the pursuit of knowledge about renal epithelial neoplasms. As a consequence of the contributions of numerous investigators over many decades, the most recent World Health Organization classification of renal neoplasms includes about 50 well defined and distinctive renal tumors, as well as various miscellaneous and metastatic tumors. In addition, a number of emerging or provisional new entities are under active investigation and may be included in future classifications. In this review, we will focus on a number of these tumors, tracing as accurately as we can the origins of their discovery, relating relevant additions to the overall knowledge base surrounding them, and in some instances addressing changes in nomenclature.

Original languageEnglish (US)
Pages (from-to)24-45
Number of pages22
JournalHuman pathology
Volume95
DOIs
StatePublished - Jan 2020

Fingerprint

Pathology
Kidney
Kidney Neoplasms
Neoplasms
Galaxies
Research Personnel
Glandular and Epithelial Neoplasms
Knowledge Bases
Terminology

Keywords

  • Classification
  • Emerging new entity
  • History
  • Kidney
  • Renal tumors

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Cite this

Five decades of urologic pathology : the accelerating expansion of knowledge in renal cell neoplasia. / MacLennan, Gregory T.; Cheng, Liang.

In: Human pathology, Vol. 95, 01.2020, p. 24-45.

Research output: Contribution to journalArticle

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