Flow cytometry derived DNA content of the primary lesions of advanced germ cell tumours

G. W. Sledge, John Eble, B. J. Roth, B. P. Wuhrman, Lawrence Einhorn

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

We currently lack good prognostic indicators for patients with advanced disseminated germ cell tumours (GCT). An analysis of archival tumour samples of forty-nine patients with advanced GCT for flow cytometry derived DNA content suggests an inverse relationship between tumour proliferative activity and patient survival. The great majority of patients with advanced GCT have aneuploid tumour subpopulation. This analysis suggests that the survival of patients with advanced GCT may depend in part on kinetic variables present in the primary tumour.

Original languageEnglish
Pages (from-to)115-120
Number of pages6
JournalInternational Journal of Andrology
Volume10
Issue number1 SPEC.
StatePublished - 1987

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Germ Cell and Embryonal Neoplasms
Flow Cytometry
DNA
Neoplasms
Aneuploidy
Survival Analysis
Survival

ASJC Scopus subject areas

  • Endocrinology

Cite this

Flow cytometry derived DNA content of the primary lesions of advanced germ cell tumours. / Sledge, G. W.; Eble, John; Roth, B. J.; Wuhrman, B. P.; Einhorn, Lawrence.

In: International Journal of Andrology, Vol. 10, No. 1 SPEC., 1987, p. 115-120.

Research output: Contribution to journalArticle

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