Fluid balance within the canine anterolateral compartment and its relationship to compartment syndromes

A. R. Hargens, W. H. Akeson, S. J. Mubarak, C. A. Owen, K. L. Evans, L. P. Garetto, M. R. Gonsalves, D. A. Schmidt

Research output: Contribution to journalArticle

113 Scopus citations

Abstract

Fluid homeostasis within muscle compartments is maintained by four pressures: capillary blood pressure, capillary blood oncotic pressure, tissue-fluid pressure, and tissue-fluid oncotic pressure. As determined in the canine anterolateral compartment, capillary blood pressure is 25 ± 3 millimeters of mercury; capillary blood oncotic pressure, 26 ± 3 millimeters of mercury; tissue-fluid pressure, -2 ± 2 millimeters of mercury; and tissue-fluid oncotic pressure, 11 ± 1 millimeters of mercury. The wick technique allows direct measurement of tissue-fluid pressure in skeletal muscle and, with minor modifications, is adapted to collect microsamples of interstitial fluid for determinations of tissue-fluid oncotic pressure. The wick technique detects very slight fluctuations in intracompartmental pressure such as light finger compression, injection of small volumes of fluid, and even pulsation due to adjacent arterial pressure. Adjacent muscle compartments may contain different tissue-fluid pressures due to impermeable osseofascial barriers. The authors' results obtained in canine muscle compartments pressurized by infusion of autologous plasma suggest that risks of muscle damage are significant at intracompartmental pressures greater than thirty millimeters of mercury.

Original languageEnglish (US)
Pages (from-to)499-505
Number of pages7
JournalUnknown Journal
Volume60
Issue number4
DOIs
StatePublished - Jan 1 1978

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine

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    Hargens, A. R., Akeson, W. H., Mubarak, S. J., Owen, C. A., Evans, K. L., Garetto, L. P., Gonsalves, M. R., & Schmidt, D. A. (1978). Fluid balance within the canine anterolateral compartment and its relationship to compartment syndromes. Unknown Journal, 60(4), 499-505. https://doi.org/10.2106/00004623-197860040-00012