Article Title and Bibliographic Information: Caries-preventive effectiveness of a fluoride varnish: a randomized controlled trial in adolescents with fixed orthodontic appliances. Stecksen-Blicks C, Renfors G, Oscarson ND, Bergstrand F, Twetman S. Caries Res 2007;41(6):455-9. Level of Evidence: Level 2: Limited-quality, patient-oriented evidence. Strength of Recommendation Grade: Not applicable. Purpose/Question: The authors aimed at evaluating the efficacy of multiple topical fluoride (F) varnish applications at preventing WSL formation in adolescents, during treatment with fixed orthodontic appliances. Source of Funding: Government and industry-With grants from the County Council of Vasterbotten (the a should have two dots above it), Sweden and the Swedish Dental Society; and with materials from Ivoclar Vivadent and 3M-Unitek. Type of Study/Design: Randomized controlled trial.
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