fMRI for preoperative neurosurgical mapping of motor cortex and language in a clinical setting

Reinhard J. Tomczak, Arthur P. Wunderlich, Yang Wang, Veit Braun, Gregor Antoniadis, Johannes Görich, Hans Peter Richter, Hans Jürgen Brambs

Research output: Contribution to journalArticle

56 Citations (Scopus)

Abstract

Purpose: Identification of the precentral gyrus can be difficult in patients with brain tumors. The purpose of the current study was to evaluate the clinical usefulness of functional MRI (fMRI) in identifying motor cortex and speech areas as a part of preoperative neurosurgical planning. Method: fMRI was performed using a 1.5 T MR unit in 41 patients with brain tumors. The motor paradigm was finger tapping and foot movement, whereas the language paradigm consisted of a two word semantic test. Statistical analysis of the data was done using the Kolmogorow-Smirnow test. Plots of signal intensities over time were created. Results: The precentral gyrus was identified in 38 of 41 patients. In two patients, fMRI was not of acceptable quality due to motion artifacts. Speech areas were localized in 33 patients. In a typical clinical setting, the value of the method was graded "high." Conclusion: fMRI's efficacy in the preoperative localization of language and motor areas is high. The method should become a routine adjunct for preoperative evaluation of brain tumors in the near future.

Original languageEnglish (US)
Pages (from-to)927-934
Number of pages8
JournalJournal of Computer Assisted Tomography
Volume24
Issue number6
DOIs
StatePublished - 2000
Externally publishedYes

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Motor Cortex
Language
Magnetic Resonance Imaging
Brain Neoplasms
Frontal Lobe
Statistical Data Interpretation
Semantics
Artifacts
Fingers
Foot

Keywords

  • Brain
  • Techniques
  • Tumor - Magnetic resonance imaging

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

fMRI for preoperative neurosurgical mapping of motor cortex and language in a clinical setting. / Tomczak, Reinhard J.; Wunderlich, Arthur P.; Wang, Yang; Braun, Veit; Antoniadis, Gregor; Görich, Johannes; Richter, Hans Peter; Brambs, Hans Jürgen.

In: Journal of Computer Assisted Tomography, Vol. 24, No. 6, 2000, p. 927-934.

Research output: Contribution to journalArticle

Tomczak, RJ, Wunderlich, AP, Wang, Y, Braun, V, Antoniadis, G, Görich, J, Richter, HP & Brambs, HJ 2000, 'fMRI for preoperative neurosurgical mapping of motor cortex and language in a clinical setting', Journal of Computer Assisted Tomography, vol. 24, no. 6, pp. 927-934. https://doi.org/10.1097/00004728-200011000-00020
Tomczak, Reinhard J. ; Wunderlich, Arthur P. ; Wang, Yang ; Braun, Veit ; Antoniadis, Gregor ; Görich, Johannes ; Richter, Hans Peter ; Brambs, Hans Jürgen. / fMRI for preoperative neurosurgical mapping of motor cortex and language in a clinical setting. In: Journal of Computer Assisted Tomography. 2000 ; Vol. 24, No. 6. pp. 927-934.
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AU - Görich, Johannes

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