Foci of increased T2 signal intensity in MR images of healthy elderly subjects. A follow-up study

Hugh Hendrie, R. F. Thompson, H. C. Hendrie, Martin Farlow, M. R. Farlow, M. K. Edwards, R. Dean

Research output: Contribution to journalArticle

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Abstract

An 18-month follow-up study was conducted on 26 healthy elderly subjects with and without foci of increased T2 signal intensity on MR imaging. The subjects did not differ with respect to health status or cognitive performance as measured by the Cognitive Subscale of the Cambridge Mental Disorders of the Elderly Examination and the Mini Mental State Examination at follow-up. There was a significant decline in performance on the Digit Symbol Substitution Test in subjects who had evidence of T2 foci compared to the performance of subjects without T2 foci. This may indicate that the presence of T2 foci is correlated with subtle difficulties in learning and memory.

Original languageEnglish
Pages (from-to)1133-1138
Number of pages6
JournalJournal of the American Geriatrics Society
Volume38
Issue number10
StatePublished - 1990

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ASJC Scopus subject areas

  • Geriatrics and Gerontology

Cite this

Hendrie, H., Thompson, R. F., Hendrie, H. C., Farlow, M., Farlow, M. R., Edwards, M. K., & Dean, R. (1990). Foci of increased T2 signal intensity in MR images of healthy elderly subjects. A follow-up study. Journal of the American Geriatrics Society, 38(10), 1133-1138.

Foci of increased T2 signal intensity in MR images of healthy elderly subjects. A follow-up study. / Hendrie, Hugh; Thompson, R. F.; Hendrie, H. C.; Farlow, Martin; Farlow, M. R.; Edwards, M. K.; Dean, R.

In: Journal of the American Geriatrics Society, Vol. 38, No. 10, 1990, p. 1133-1138.

Research output: Contribution to journalArticle

Hendrie, Hugh ; Thompson, R. F. ; Hendrie, H. C. ; Farlow, Martin ; Farlow, M. R. ; Edwards, M. K. ; Dean, R. / Foci of increased T2 signal intensity in MR images of healthy elderly subjects. A follow-up study. In: Journal of the American Geriatrics Society. 1990 ; Vol. 38, No. 10. pp. 1133-1138.
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