Forced expiratory flows and lung volumes in normal infants

Robert S. Tepper, Teresa Reister, C. Angelicchio‐Keller, J. Kisling

Research output: Contribution to journalArticle

77 Scopus citations


Forced expiratory flows at functional residual capacity (VmaxFRC) by the rapid compression technique and functional residual capacity (FRC) by the helium dilution technique were assessed in 112 normal infants with a mean age of 10.7 months (range, 1.0-31.0). In predicting FRC, log transformation was appropriate and body length was the best predicator. For VmaxFRC, age was a better predictor than length, and logarithmic transformation was not required. In(FRC) = -5.465 + 2.49 x In(length) SD = 0.178; r2 = 0.83 VmaxFRC = -397 + 9.36 x (age) SD = 88; r2 = 0.52 There were no gender differences for FRC or VmaxFRC; however, male infants exposed to passive cigarette smoke tended to have lower flows than male infants not exposed (P < 0.07). This study establishes normative values for VmaxFRC and FRC in infants between 1 and 31 months of age, and suggests that passive cigarette smoke exposure has an adverse effect upon forced expiratory flows in male infants.

Original languageEnglish (US)
Pages (from-to)357-361
Number of pages5
JournalPediatric pulmonology
Issue number6
StatePublished - Jun 1993


  • Rapid compression technique
  • age, length
  • gender
  • helium dilution
  • passive smoking

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Pulmonary and Respiratory Medicine

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