Fragile X syndrome

John P. Phillips, Gregory A. Wilson

    Research output: Contribution to journalArticle

    1 Scopus citations

    Abstract

    Fragile X syndrome is the most common form of inherited mental retardation. It is seen in people of all nationalities and in all areas of the world. Fragile X syndrome can be a devastating condition, as many boys are severely retarded and require multiple services. Treatment involves behaviour management techniques, appropriate school placement, community support for the family, and careful medical follow-up often including psychopharmacology. The genetics of fragile X syndrome is now understood, prenatal testing is available, and the disorder is preventable through appropriate genetic counselling. This review focuses on the neurobiology of fragile X syndrome, its clinical features and treatment.

    Original languageEnglish (US)
    Pages (from-to)181-191
    Number of pages11
    JournalIndian journal of pediatrics
    Volume65
    Issue number2
    DOIs
    StatePublished - Jan 1 1998

    Keywords

    • Fragile X syndrome
    • Martin-Bell syndrome
    • Mental retardation
    • Trinucleotide repeat

    ASJC Scopus subject areas

    • Pediatrics, Perinatology, and Child Health

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  • Cite this

    Phillips, J. P., & Wilson, G. A. (1998). Fragile X syndrome. Indian journal of pediatrics, 65(2), 181-191. https://doi.org/10.1007/BF02752293