Abstract
Sickle cell genotype prevalence was 26% in a malaria-holoendemic lowland area compared with 3% in a highland area of Kenya. The prevalence of glucose-6-phosphate dehydrogenase deficiency was 7% and 1 % in holoendemic lowland and highland areas, respectively. Lack of protective polymorphisms may contribute to morbidity and mortality during outbreaks of malaria in the highlands.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 513-514 |
| Number of pages | 2 |
| Journal | Transactions of the Royal Society of Tropical Medicine and Hygiene |
| Volume | 97 |
| Issue number | 5 |
| DOIs | |
| State | Published - Sep 1 2003 |
| Externally published | Yes |
Keywords
- Glucose-6-phosphate dehydrogenase
- Kenya
- Malaria
- Plasmodium falciparum
- Sickle cell trait
ASJC Scopus subject areas
- Parasitology
- Public Health, Environmental and Occupational Health
- Infectious Diseases
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Cite this
Moormann, A. M., Embury, P. E., Opondo, J., Sumba, O. P., Ouma, J. H., Kazura, J. W., & John, C. C. (2003). Frequencies of sickle cell trait and glucose-6-phosphate dehydrogenase deficiency differ in highland and nearby lowland malaria-endemic areas of Kenya. Transactions of the Royal Society of Tropical Medicine and Hygiene, 97(5), 513-514. https://doi.org/10.1016/S0035-9203(03)80010-X