Abstract
Sickle cell genotype prevalence was 26% in a malaria-holoendemic lowland area compared with 3% in a highland area of Kenya. The prevalence of glucose-6-phosphate dehydrogenase deficiency was 7% and 1 % in holoendemic lowland and highland areas, respectively. Lack of protective polymorphisms may contribute to morbidity and mortality during outbreaks of malaria in the highlands.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 513-514 |
| Number of pages | 2 |
| Journal | Transactions of the Royal Society of Tropical Medicine and Hygiene |
| Volume | 97 |
| Issue number | 5 |
| DOIs | |
| State | Published - Sep 2003 |
| Externally published | Yes |
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Keywords
- Glucose-6-phosphate dehydrogenase
- Kenya
- Malaria
- Plasmodium falciparum
- Sickle cell trait
ASJC Scopus subject areas
- Parasitology
- Medicine(all)
Cite this
Frequencies of sickle cell trait and glucose-6-phosphate dehydrogenase deficiency differ in highland and nearby lowland malaria-endemic areas of Kenya. / Moormann, A. M.; Embury, P. E.; Opondo, J.; Sumba, O. P.; Ouma, J. H.; Kazura, J. W.; John, Chandy.
In: Transactions of the Royal Society of Tropical Medicine and Hygiene, Vol. 97, No. 5, 09.2003, p. 513-514.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Frequencies of sickle cell trait and glucose-6-phosphate dehydrogenase deficiency differ in highland and nearby lowland malaria-endemic areas of Kenya
AU - Moormann, A. M.
AU - Embury, P. E.
AU - Opondo, J.
AU - Sumba, O. P.
AU - Ouma, J. H.
AU - Kazura, J. W.
AU - John, Chandy
PY - 2003/9
Y1 - 2003/9
N2 - Sickle cell genotype prevalence was 26% in a malaria-holoendemic lowland area compared with 3% in a highland area of Kenya. The prevalence of glucose-6-phosphate dehydrogenase deficiency was 7% and 1 % in holoendemic lowland and highland areas, respectively. Lack of protective polymorphisms may contribute to morbidity and mortality during outbreaks of malaria in the highlands.
AB - Sickle cell genotype prevalence was 26% in a malaria-holoendemic lowland area compared with 3% in a highland area of Kenya. The prevalence of glucose-6-phosphate dehydrogenase deficiency was 7% and 1 % in holoendemic lowland and highland areas, respectively. Lack of protective polymorphisms may contribute to morbidity and mortality during outbreaks of malaria in the highlands.
KW - Glucose-6-phosphate dehydrogenase
KW - Kenya
KW - Malaria
KW - Plasmodium falciparum
KW - Sickle cell trait
UR - http://www.scopus.com/inward/record.url?scp=7244239182&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=7244239182&partnerID=8YFLogxK
U2 - 10.1016/S0035-9203(03)80010-X
DO - 10.1016/S0035-9203(03)80010-X
M3 - Article
C2 - 15307413
AN - SCOPUS:7244239182
VL - 97
SP - 513
EP - 514
JO - Transactions of the Royal Society of Tropical Medicine and Hygiene
JF - Transactions of the Royal Society of Tropical Medicine and Hygiene
SN - 0035-9203
IS - 5
ER -