Fully automated synthesis and initial PET evaluation of [11C]PBR28

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Abstract

Fully automated synthesis and initial PET evaluation of a TSPO radioligand, [11C]PBR28 (N-(2-[11C]methoxybenzyl)-N-(4-phenoxypyridin-3-yl)acetamide), are reported. These results facilitate the potential preclinical and clinical PET studies of [11C]PBR28 in animals and humans.

Original languageEnglish (US)
Pages (from-to)5636-5639
Number of pages4
JournalBioorganic and Medicinal Chemistry Letters
Volume19
Issue number19
DOIs
StatePublished - Oct 1 2009

Cite this

Fully automated synthesis and initial PET evaluation of [11C]PBR28. / Wang, Min; Yoder, Karmen K.; Gao, Mingzhang; Mock, Bruce H.; Xu, Xiao Ming; Saykin, Andrew J.; Hutchins, Gary D.; Zheng, Qi Huang.

In: Bioorganic and Medicinal Chemistry Letters, Vol. 19, No. 19, 01.10.2009, p. 5636-5639.

Research output: Contribution to journalArticle