Functional gastrointestinal disorders: Past and present

Research output: Contribution to journalReview article

15 Scopus citations


Background: Chronic abdominal pain is a common complaint in childhood and adolescence. Despite decades of clinical observations and research, it still poses a challenge to pediatric health care professionals. The aim of this review is to highlight the epidemiology of pediatric chronic abdominal pain and to describe the pathogenesis of this disorder, its clinical manifestations, evaluation and therapeutic options. Data sources: Articles on chronic abdominal pain in the recent years from PubMed, MEDLINE, and reference textbooks were reviewed. Results: Chronic abdominal pain, a functional gastrointestinal disorder (FGID), is a multifactorial condition that results from a complex interaction between psychosocial and physiologic factors via the brain-gut axis. A thorough history coupled with a complete physical examination and normal screening studies rule out an organic cause in 95% of the cases. It is highly important for the physician to establish a trusting relationship with the child and parents because successful treatment including modification of physical and psychological stress factors, dietary changes, and drug therapy depends greatly on education, reassurance and active psychological support. Conclusions: FGIDs are a cause of great anxiety, distress and morbidity in children as well as adults. As our understanding of these conditions improves, our therapeutic interventions will progress not only to overcome them but also to intervene early in the disease course so as to limit long-term impact.

Original languageEnglish (US)
Pages (from-to)103-112
Number of pages10
JournalWorld Journal of Pediatrics
Issue number2
StatePublished - Jul 27 2009


  • Abdominal pain
  • Bowel syndrome
  • Gastrointestinal disorders

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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