Functionalized liposome purification via Liposome Extruder Purification (LEP)

Nathan Alves, William Cusick, Jared F. Stefanick, Jonathan D. Ashley, Michael W. Handlogten, Basar Bilgicer

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Liposome Extruder Purification (LEP) allows for the rapid purification of diverse liposome formulations using the same extrusion apparatus employed during liposome formation. The LEP process provides a means for purifying functionalized liposomes from non-conjugated drug or protein contaminants with >93% liposome recovery and >93% contaminant removal in a single step.

Original languageEnglish (US)
Pages (from-to)4746-4751
Number of pages6
JournalAnalyst
Volume138
Issue number17
DOIs
StatePublished - 2013
Externally publishedYes

Fingerprint

Liposomes
Extruders
Purification
purification
pollutant
extrusion
drug
Impurities
protein
Extrusion
Proteins
Recovery
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Analytical Chemistry
  • Spectroscopy
  • Electrochemistry
  • Biochemistry
  • Environmental Chemistry

Cite this

Alves, N., Cusick, W., Stefanick, J. F., Ashley, J. D., Handlogten, M. W., & Bilgicer, B. (2013). Functionalized liposome purification via Liposome Extruder Purification (LEP). Analyst, 138(17), 4746-4751. https://doi.org/10.1039/c3an00680h

Functionalized liposome purification via Liposome Extruder Purification (LEP). / Alves, Nathan; Cusick, William; Stefanick, Jared F.; Ashley, Jonathan D.; Handlogten, Michael W.; Bilgicer, Basar.

In: Analyst, Vol. 138, No. 17, 2013, p. 4746-4751.

Research output: Contribution to journalArticle

Alves, N, Cusick, W, Stefanick, JF, Ashley, JD, Handlogten, MW & Bilgicer, B 2013, 'Functionalized liposome purification via Liposome Extruder Purification (LEP)', Analyst, vol. 138, no. 17, pp. 4746-4751. https://doi.org/10.1039/c3an00680h
Alves N, Cusick W, Stefanick JF, Ashley JD, Handlogten MW, Bilgicer B. Functionalized liposome purification via Liposome Extruder Purification (LEP). Analyst. 2013;138(17):4746-4751. https://doi.org/10.1039/c3an00680h
Alves, Nathan ; Cusick, William ; Stefanick, Jared F. ; Ashley, Jonathan D. ; Handlogten, Michael W. ; Bilgicer, Basar. / Functionalized liposome purification via Liposome Extruder Purification (LEP). In: Analyst. 2013 ; Vol. 138, No. 17. pp. 4746-4751.
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