GABAA receptor β2/β3 subunit and GAD67 immunoreactivity in the trigeminal motor nucleus during early postnatal development

Jack Turman, R. A. Rich, S. H. Chandler

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

GABA neurotransmission plays a role in brainstem circuitry responsible for jaw movements. We investigated the developmental relationship between terminals expressing GAD67 and GABAA receptor β23 subunit expression within the trigeminal motor nucleus. GAD67 immunoreactivity was intense throughout development. Neuropilar β23 immunoreactivity emerged during the 2nd postnatal week. Our data provide anatomical evidence for a GABAergic innervation of neonatal trigeminal motoneurons and suggest that β23 subunit expression is developmentally regulated in trigeminal motoneurons.

Original languageEnglish (US)
Pages (from-to)155-158
Number of pages4
JournalDevelopmental Brain Research
Volume130
Issue number1
DOIs
StatePublished - Sep 23 2001
Externally publishedYes

Fingerprint

Motor Neurons
GABA-A Receptors
Jaw
Synaptic Transmission
gamma-Aminobutyric Acid
Brain Stem
Trigeminal Motor Nucleus

Keywords

  • Jaw
  • Motoneuron
  • Suckling

ASJC Scopus subject areas

  • Developmental Neuroscience
  • Developmental Biology

Cite this

GABAA receptor β2/β3 subunit and GAD67 immunoreactivity in the trigeminal motor nucleus during early postnatal development. / Turman, Jack; Rich, R. A.; Chandler, S. H.

In: Developmental Brain Research, Vol. 130, No. 1, 23.09.2001, p. 155-158.

Research output: Contribution to journalArticle

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