GABAA receptor β2/β3 subunit and GAD67 immunoreactivity in the trigeminal motor nucleus during early postnatal development

J. Turman, R. A. Rich, S. H. Chandler

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

GABA neurotransmission plays a role in brainstem circuitry responsible for jaw movements. We investigated the developmental relationship between terminals expressing GAD67 and GABAA receptor β23 subunit expression within the trigeminal motor nucleus. GAD67 immunoreactivity was intense throughout development. Neuropilar β23 immunoreactivity emerged during the 2nd postnatal week. Our data provide anatomical evidence for a GABAergic innervation of neonatal trigeminal motoneurons and suggest that β23 subunit expression is developmentally regulated in trigeminal motoneurons.

Original languageEnglish (US)
Pages (from-to)155-158
Number of pages4
JournalDevelopmental Brain Research
Volume130
Issue number1
DOIs
StatePublished - Sep 23 2001
Externally publishedYes

Keywords

  • Jaw
  • Motoneuron
  • Suckling

ASJC Scopus subject areas

  • Developmental Neuroscience
  • Developmental Biology

Fingerprint Dive into the research topics of 'GABA<sub>A</sub> receptor β2/β3 subunit and GAD67 immunoreactivity in the trigeminal motor nucleus during early postnatal development'. Together they form a unique fingerprint.

  • Cite this