Gastrointestinal plasmacytoma presenting as gastrointestinal bleeding

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5 Citations (Scopus)

Abstract

Clinical manifestations of gastrointestinal (GI) involvement in multiple myeloma (MM) are uncommon. We report a case of plasmacytoma presenting as upper GI bleeding in a patient with a known diagnosis of MM. Gastrointestinal bleeding persists despite aggressive medical and endoscopic treatment. The aim of our report is to heighten the awareness of plasmacytoma as an etiology of GI bleeding in patients with MM. Abnormal hemostasis, specifically the imbalance in function of all major components of the coagulation cascade, increasing bleeding risk in patients with MM, is also discussed.

Original languageEnglish
Pages (from-to)309-311
Number of pages3
JournalClinical Lymphoma and Myeloma
Volume8
Issue number5
DOIs
StatePublished - Oct 1 2008

Fingerprint

Plasmacytoma
Multiple Myeloma
Hemorrhage
Hemostasis
Therapeutics

Keywords

  • Doxorubicin
  • Endoscopy
  • Immunoglobulin
  • Multiple myeloma
  • Ulceration

ASJC Scopus subject areas

  • Cancer Research
  • Oncology
  • Hematology

Cite this

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title = "Gastrointestinal plasmacytoma presenting as gastrointestinal bleeding",
abstract = "Clinical manifestations of gastrointestinal (GI) involvement in multiple myeloma (MM) are uncommon. We report a case of plasmacytoma presenting as upper GI bleeding in a patient with a known diagnosis of MM. Gastrointestinal bleeding persists despite aggressive medical and endoscopic treatment. The aim of our report is to heighten the awareness of plasmacytoma as an etiology of GI bleeding in patients with MM. Abnormal hemostasis, specifically the imbalance in function of all major components of the coagulation cascade, increasing bleeding risk in patients with MM, is also discussed.",
keywords = "Doxorubicin, Endoscopy, Immunoglobulin, Multiple myeloma, Ulceration",
author = "Attaya Suvannasankha and Rafat Abonour and Oscar Cummings and Suthat Liangpunsakul",
year = "2008",
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T1 - Gastrointestinal plasmacytoma presenting as gastrointestinal bleeding

AU - Suvannasankha, Attaya

AU - Abonour, Rafat

AU - Cummings, Oscar

AU - Liangpunsakul, Suthat

PY - 2008/10/1

Y1 - 2008/10/1

N2 - Clinical manifestations of gastrointestinal (GI) involvement in multiple myeloma (MM) are uncommon. We report a case of plasmacytoma presenting as upper GI bleeding in a patient with a known diagnosis of MM. Gastrointestinal bleeding persists despite aggressive medical and endoscopic treatment. The aim of our report is to heighten the awareness of plasmacytoma as an etiology of GI bleeding in patients with MM. Abnormal hemostasis, specifically the imbalance in function of all major components of the coagulation cascade, increasing bleeding risk in patients with MM, is also discussed.

AB - Clinical manifestations of gastrointestinal (GI) involvement in multiple myeloma (MM) are uncommon. We report a case of plasmacytoma presenting as upper GI bleeding in a patient with a known diagnosis of MM. Gastrointestinal bleeding persists despite aggressive medical and endoscopic treatment. The aim of our report is to heighten the awareness of plasmacytoma as an etiology of GI bleeding in patients with MM. Abnormal hemostasis, specifically the imbalance in function of all major components of the coagulation cascade, increasing bleeding risk in patients with MM, is also discussed.

KW - Doxorubicin

KW - Endoscopy

KW - Immunoglobulin

KW - Multiple myeloma

KW - Ulceration

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JO - Clinical Lymphoma, Myeloma and Leukemia

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