Gd-DTPA-enhanced MR imaging of leptomeningeal spread of primary intracranial CNS tumor in children

D. J. Rippe, Orest Boyko, H. S. Friedman, W. J. Oakes, S. C. Schold, G. R. DeLong, W. J. Meisler

Research output: Contribution to journalArticle

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Abstract

Three children with known primary brain neoplasms and leptomeningeal disease were evaluated with MR imaging. Two of the patients had medulloblastoma and one had pineoblastoma. The presence of leptomeningeal tumor spread was established by positive CSF cytopathology in conjunction with compatible contrast-enhanced CT findings. Contrast-enhanced CT, nonenhanced MR, and Gd-DTPA-enhanced MR studies were then compared. In two cases, leptomeningeal lesions were seen better with Gd-DTPA-enhanced MR than with contrast-enhanced CT. In all three cases, Gd-DTPA MR imaging revealed lesions that were not identified on noncontrast MR. Gd-DTPA-enhanced MR imaging is useful when searching for intracranial leptomeningeal tumor deposits in pediatric patients at risk for this condition.

Original languageEnglish (US)
Pages (from-to)329-332
Number of pages4
JournalAmerican Journal of Neuroradiology
Volume11
Issue number2
StatePublished - 1990
Externally publishedYes

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Gadolinium DTPA
Neoplasms
Pinealoma
Medulloblastoma
Brain Neoplasms
Pediatrics

ASJC Scopus subject areas

  • Clinical Neurology
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Rippe, D. J., Boyko, O., Friedman, H. S., Oakes, W. J., Schold, S. C., DeLong, G. R., & Meisler, W. J. (1990). Gd-DTPA-enhanced MR imaging of leptomeningeal spread of primary intracranial CNS tumor in children. American Journal of Neuroradiology, 11(2), 329-332.

Gd-DTPA-enhanced MR imaging of leptomeningeal spread of primary intracranial CNS tumor in children. / Rippe, D. J.; Boyko, Orest; Friedman, H. S.; Oakes, W. J.; Schold, S. C.; DeLong, G. R.; Meisler, W. J.

In: American Journal of Neuroradiology, Vol. 11, No. 2, 1990, p. 329-332.

Research output: Contribution to journalArticle

Rippe, DJ, Boyko, O, Friedman, HS, Oakes, WJ, Schold, SC, DeLong, GR & Meisler, WJ 1990, 'Gd-DTPA-enhanced MR imaging of leptomeningeal spread of primary intracranial CNS tumor in children', American Journal of Neuroradiology, vol. 11, no. 2, pp. 329-332.
Rippe DJ, Boyko O, Friedman HS, Oakes WJ, Schold SC, DeLong GR et al. Gd-DTPA-enhanced MR imaging of leptomeningeal spread of primary intracranial CNS tumor in children. American Journal of Neuroradiology. 1990;11(2):329-332.
Rippe, D. J. ; Boyko, Orest ; Friedman, H. S. ; Oakes, W. J. ; Schold, S. C. ; DeLong, G. R. ; Meisler, W. J. / Gd-DTPA-enhanced MR imaging of leptomeningeal spread of primary intracranial CNS tumor in children. In: American Journal of Neuroradiology. 1990 ; Vol. 11, No. 2. pp. 329-332.
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