Gene expression in brain: A window on ethanol dependence, neuroadaptation, and preference

Paula L. Hoffman, Michael Miles, Howard Edenberg, Wolfgang Sommer, Boris Tabakoff, Jeanne M. Wehner, Joanne Lewohl

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

This article represents the proceedings of a symposium at the 2002 joint RSA/ISBRA Conference in San Francisco, California. The organizer was Paula L. Hoffman and the co-chairs were Paula L. Hoffman and Michael Miles. The presentations were (1) Introduction and overview of the use of DNA microarrays, by Michael Miles; (2) DNA microarray analysis of gene expression in brains of P and NP rats, by Howard J. Edenberg; (3) Gene expression patterns in brain regions of AA and ANA rats, by Wolfgang Sommer; (4) Patterns of gene expression in brains of selected lines of mice that differ in ethanol tolerance, by Boris Tabakoff; (5) Gene expression profiling related to initial sensitivity and tolerance in gamma-protein kinase C mutants, by Jeanne Wehner; and (6) Gene expression patterns in human alcoholic brain: from microarrays to protein profiles, by Joanne Lewohl.

Original languageEnglish
Pages (from-to)155-168
Number of pages14
JournalAlcoholism: Clinical and Experimental Research
Volume27
Issue number2
DOIs
StatePublished - Feb 1 2003

Fingerprint

Gene expression
Brain
Ethanol
Gene Expression
Microarrays
Oligonucleotide Array Sequence Analysis
Rats
Protein Array Analysis
San Francisco
Gene Expression Profiling
Microarray Analysis
DNA
Joints
Proteins

Keywords

  • Alcohol preference
  • Alcohol tolerance
  • Alcoholism
  • DNA microarrays
  • Gene expression
  • Null mutants
  • Selected lines
  • Transgenics

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Toxicology

Cite this

Gene expression in brain : A window on ethanol dependence, neuroadaptation, and preference. / Hoffman, Paula L.; Miles, Michael; Edenberg, Howard; Sommer, Wolfgang; Tabakoff, Boris; Wehner, Jeanne M.; Lewohl, Joanne.

In: Alcoholism: Clinical and Experimental Research, Vol. 27, No. 2, 01.02.2003, p. 155-168.

Research output: Contribution to journalArticle

Hoffman, Paula L. ; Miles, Michael ; Edenberg, Howard ; Sommer, Wolfgang ; Tabakoff, Boris ; Wehner, Jeanne M. ; Lewohl, Joanne. / Gene expression in brain : A window on ethanol dependence, neuroadaptation, and preference. In: Alcoholism: Clinical and Experimental Research. 2003 ; Vol. 27, No. 2. pp. 155-168.
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