Genes contributing to the development of alcoholism: an overview

Research output: Contribution to journalEditorial

5 Scopus citations

Abstract

Genetic factors (i.e., variations in specific genes) account for a substantial portion of the risk for alcoholism. However, identifying those genes and the specific variations involved is challenging. Researchers have used both case-control and family studies to identify genes related to alcoholism risk. In addition, different strategies such as candidate gene analyses and genome-wide association studies have been used. The strongest effects have been found for specific variants of genes that encode two enzymes involved in alcohol metabolism-alcohol dehydrogenase and aldehyde dehydrogenase. Accumulating evidence indicates that variations in numerous other genes have smaller but measurable effects.

Original languageEnglish (US)
Pages (from-to)336-338
Number of pages3
JournalAlcohol research : current reviews
Volume34
Issue number3
StatePublished - 2012

ASJC Scopus subject areas

  • Medicine(all)

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