Genetic and bioinformatic tools in Parkinson’s disease

Tatiana Foroud, Nathan Pankratz

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

For many years, Parkinson’s disease (PD) was thought to be strictly inŸuenced by environmental factors without a substantial genetic contribution to disease etiology. However, studies from around the world have provided evidence that genetic risk factors are involved in the pathogenesis of the idiopathic form of PD. Estimates of the relative risk to firstdegree relatives of an affected individual range from 2.7 to 3.5 in the United States,1,2 2.9 in Finland,3 6.7 in Iceland,4 7.7 in France,5 3.2 in three centers within Europe,6 5.0 in Canada,7 13.4 in Italy,8 and 7.1 in Germany.9.

Original languageEnglish (US)
Title of host publicationParkinson's Disease, Second Edition
PublisherCRC Press
Pages181-187
Number of pages7
ISBN (Electronic)9781439807156
ISBN (Print)9781439807149
DOIs
StatePublished - Jan 1 2012

Fingerprint

Computational Biology
Parkinson Disease
Iceland
Finland
Italy
France
Canada

ASJC Scopus subject areas

  • Neuroscience(all)
  • Medicine(all)

Cite this

Foroud, T., & Pankratz, N. (2012). Genetic and bioinformatic tools in Parkinson’s disease. In Parkinson's Disease, Second Edition (pp. 181-187). CRC Press. https://doi.org/10.1201/b12948

Genetic and bioinformatic tools in Parkinson’s disease. / Foroud, Tatiana; Pankratz, Nathan.

Parkinson's Disease, Second Edition. CRC Press, 2012. p. 181-187.

Research output: Chapter in Book/Report/Conference proceedingChapter

Foroud, T & Pankratz, N 2012, Genetic and bioinformatic tools in Parkinson’s disease. in Parkinson's Disease, Second Edition. CRC Press, pp. 181-187. https://doi.org/10.1201/b12948
Foroud T, Pankratz N. Genetic and bioinformatic tools in Parkinson’s disease. In Parkinson's Disease, Second Edition. CRC Press. 2012. p. 181-187 https://doi.org/10.1201/b12948
Foroud, Tatiana ; Pankratz, Nathan. / Genetic and bioinformatic tools in Parkinson’s disease. Parkinson's Disease, Second Edition. CRC Press, 2012. pp. 181-187
@inbook{e9c1e034cf3b4968b76530f6520a1334,
title = "Genetic and bioinformatic tools in Parkinson’s disease",
abstract = "For many years, Parkinson’s disease (PD) was thought to be strictly inŸuenced by environmental factors without a substantial genetic contribution to disease etiology. However, studies from around the world have provided evidence that genetic risk factors are involved in the pathogenesis of the idiopathic form of PD. Estimates of the relative risk to firstdegree relatives of an affected individual range from 2.7 to 3.5 in the United States,1,2 2.9 in Finland,3 6.7 in Iceland,4 7.7 in France,5 3.2 in three centers within Europe,6 5.0 in Canada,7 13.4 in Italy,8 and 7.1 in Germany.9.",
author = "Tatiana Foroud and Nathan Pankratz",
year = "2012",
month = "1",
day = "1",
doi = "10.1201/b12948",
language = "English (US)",
isbn = "9781439807149",
pages = "181--187",
booktitle = "Parkinson's Disease, Second Edition",
publisher = "CRC Press",

}

TY - CHAP

T1 - Genetic and bioinformatic tools in Parkinson’s disease

AU - Foroud, Tatiana

AU - Pankratz, Nathan

PY - 2012/1/1

Y1 - 2012/1/1

N2 - For many years, Parkinson’s disease (PD) was thought to be strictly inŸuenced by environmental factors without a substantial genetic contribution to disease etiology. However, studies from around the world have provided evidence that genetic risk factors are involved in the pathogenesis of the idiopathic form of PD. Estimates of the relative risk to firstdegree relatives of an affected individual range from 2.7 to 3.5 in the United States,1,2 2.9 in Finland,3 6.7 in Iceland,4 7.7 in France,5 3.2 in three centers within Europe,6 5.0 in Canada,7 13.4 in Italy,8 and 7.1 in Germany.9.

AB - For many years, Parkinson’s disease (PD) was thought to be strictly inŸuenced by environmental factors without a substantial genetic contribution to disease etiology. However, studies from around the world have provided evidence that genetic risk factors are involved in the pathogenesis of the idiopathic form of PD. Estimates of the relative risk to firstdegree relatives of an affected individual range from 2.7 to 3.5 in the United States,1,2 2.9 in Finland,3 6.7 in Iceland,4 7.7 in France,5 3.2 in three centers within Europe,6 5.0 in Canada,7 13.4 in Italy,8 and 7.1 in Germany.9.

UR - http://www.scopus.com/inward/record.url?scp=85055799670&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85055799670&partnerID=8YFLogxK

U2 - 10.1201/b12948

DO - 10.1201/b12948

M3 - Chapter

AN - SCOPUS:85055799670

SN - 9781439807149

SP - 181

EP - 187

BT - Parkinson's Disease, Second Edition

PB - CRC Press

ER -