Genetic and neurobiological basis of alcohol-seeking behavior

Ting Kai Li, Lawrence Lumeng, William J. Mcbride, James M. Murphy

Research output: Contribution to journalArticle

40 Scopus citations

Abstract

Through selective breeding, rat lines exhibiting high and low alcohol drinking preference have been developed as useful animal models for studying the neurobiological basis of alcohol-seeking behavior. The identified differences between lines in neurotransmitter functioning allows the evaluation of receptor agonist/antagonist compounds that might be efficacious in the treatment of alcohol craving and dependendence.

Original languageEnglish (US)
Pages (from-to)697-700
Number of pages4
JournalAlcohol and Alcoholism
Volume29
Issue number6
StatePublished - Nov 1 1994

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Toxicology
  • Psychiatry and Mental health

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  • Cite this

    Li, T. K., Lumeng, L., Mcbride, W. J., & Murphy, J. M. (1994). Genetic and neurobiological basis of alcohol-seeking behavior. Alcohol and Alcoholism, 29(6), 697-700.