Through selective breeding, rat lines exhibiting high and low alcohol drinking preference have been developed as useful animal models for studying the neurobiological basis of alcohol-seeking behavior. The identified differences between lines in neurotransmitter functioning allows the evaluation of receptor agonist/antagonist compounds that might be efficacious in the treatment of alcohol craving and dependendence.
|Original language||English (US)|
|Number of pages||4|
|Journal||Alcohol and Alcoholism|
|State||Published - Nov 1 1994|
ASJC Scopus subject areas
- Medicine (miscellaneous)
- Psychiatry and Mental health