Genetic strategies to detect genes involved in alcoholism and alcohol-related traits

Danielle M. Dick, Tatiana Foroud

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Researchers are using a variety of sophisticated approaches to identify genes that contribute to the development of alcoholism in humans or influence other alcohol-related traits. These strategies include linkage approaches, which can identify broad chromosomal regions that are likely to contain genes predisposing to the disorder, and association approaches, which test the association between a particular marker allele and a specific outcome. Animal studies using diverse strategies can also help identify genes or DNA regions that influence alcohol-related traits in humans. The results of these analyses are likely to have implications for fields such as genetic counseling, gene therapy, and pharmacogenetics.

Original languageEnglish
Pages (from-to)172-180
Number of pages9
JournalAlcohol Research and Health
Volume26
Issue number3
StatePublished - 2002

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Alcoholism
Alcohols
Genes
Pharmacogenetics
Genetic Counseling
Genetic Therapy
Alleles
Research Personnel
DNA

Keywords

  • Alcoholic beverage
  • AOD dependence potential
  • DNA
  • Genetic correlation analysis
  • Genetic linkage
  • Genetic screening method
  • Genetic theory of AODU (alcohol and other drug use)
  • Genetic trait
  • Genome
  • Mutation
  • QTL (quantitative trait locus) mapping

ASJC Scopus subject areas

  • Medicine (miscellaneous)

Cite this

Genetic strategies to detect genes involved in alcoholism and alcohol-related traits. / Dick, Danielle M.; Foroud, Tatiana.

In: Alcohol Research and Health, Vol. 26, No. 3, 2002, p. 172-180.

Research output: Contribution to journalArticle

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