Genitourinary neurofibromatosis in childhood

R. C. Rink, M. E. Mitchell

Research output: Contribution to journalArticle

40 Citations (Scopus)

Abstract

Neurofibromatosis in children occurs uncommonly and involvement of the bladder is exceedingly rare. The syndrome is transmitted as an autosomal dominant trait and is characterized by cutaneous pigmentation and tumors of neural crest origin. Hypertension has been documented in association with neurofibromatosis in the form of renovascular disease in children and with pheochromocytomas in adults. We report on 2 children with extensive neurofibromas of the bladder, upper tract damage and genital enlargement. One case was misdiagnosed as posterior urethral valves and the other case as clitoral hypertrophy. The literature of urogenital neurofibromatosis is reviewed with particular attention to bladder lesions, hypertension, malignant potential and treatment options.

Original languageEnglish
Pages (from-to)1176-1179
Number of pages4
JournalJournal of Urology
Volume130
Issue number6
StatePublished - 1983

Fingerprint

Neurofibromatoses
Urinary Bladder
Malignant Hypertension
Skin Pigmentation
Neurofibroma
Pheochromocytoma
Diagnostic Errors
Hypertrophy
Hypertension
Therapeutics

ASJC Scopus subject areas

  • Urology

Cite this

Rink, R. C., & Mitchell, M. E. (1983). Genitourinary neurofibromatosis in childhood. Journal of Urology, 130(6), 1176-1179.

Genitourinary neurofibromatosis in childhood. / Rink, R. C.; Mitchell, M. E.

In: Journal of Urology, Vol. 130, No. 6, 1983, p. 1176-1179.

Research output: Contribution to journalArticle

Rink, RC & Mitchell, ME 1983, 'Genitourinary neurofibromatosis in childhood', Journal of Urology, vol. 130, no. 6, pp. 1176-1179.
Rink RC, Mitchell ME. Genitourinary neurofibromatosis in childhood. Journal of Urology. 1983;130(6):1176-1179.
Rink, R. C. ; Mitchell, M. E. / Genitourinary neurofibromatosis in childhood. In: Journal of Urology. 1983 ; Vol. 130, No. 6. pp. 1176-1179.
@article{5e30c55d4c0a4fd095b423616e9ce3e2,
title = "Genitourinary neurofibromatosis in childhood",
abstract = "Neurofibromatosis in children occurs uncommonly and involvement of the bladder is exceedingly rare. The syndrome is transmitted as an autosomal dominant trait and is characterized by cutaneous pigmentation and tumors of neural crest origin. Hypertension has been documented in association with neurofibromatosis in the form of renovascular disease in children and with pheochromocytomas in adults. We report on 2 children with extensive neurofibromas of the bladder, upper tract damage and genital enlargement. One case was misdiagnosed as posterior urethral valves and the other case as clitoral hypertrophy. The literature of urogenital neurofibromatosis is reviewed with particular attention to bladder lesions, hypertension, malignant potential and treatment options.",
author = "Rink, {R. C.} and Mitchell, {M. E.}",
year = "1983",
language = "English",
volume = "130",
pages = "1176--1179",
journal = "Journal of Urology",
issn = "0022-5347",
publisher = "Elsevier Inc.",
number = "6",

}

TY - JOUR

T1 - Genitourinary neurofibromatosis in childhood

AU - Rink, R. C.

AU - Mitchell, M. E.

PY - 1983

Y1 - 1983

N2 - Neurofibromatosis in children occurs uncommonly and involvement of the bladder is exceedingly rare. The syndrome is transmitted as an autosomal dominant trait and is characterized by cutaneous pigmentation and tumors of neural crest origin. Hypertension has been documented in association with neurofibromatosis in the form of renovascular disease in children and with pheochromocytomas in adults. We report on 2 children with extensive neurofibromas of the bladder, upper tract damage and genital enlargement. One case was misdiagnosed as posterior urethral valves and the other case as clitoral hypertrophy. The literature of urogenital neurofibromatosis is reviewed with particular attention to bladder lesions, hypertension, malignant potential and treatment options.

AB - Neurofibromatosis in children occurs uncommonly and involvement of the bladder is exceedingly rare. The syndrome is transmitted as an autosomal dominant trait and is characterized by cutaneous pigmentation and tumors of neural crest origin. Hypertension has been documented in association with neurofibromatosis in the form of renovascular disease in children and with pheochromocytomas in adults. We report on 2 children with extensive neurofibromas of the bladder, upper tract damage and genital enlargement. One case was misdiagnosed as posterior urethral valves and the other case as clitoral hypertrophy. The literature of urogenital neurofibromatosis is reviewed with particular attention to bladder lesions, hypertension, malignant potential and treatment options.

UR - http://www.scopus.com/inward/record.url?scp=0021016589&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0021016589&partnerID=8YFLogxK

M3 - Article

VL - 130

SP - 1176

EP - 1179

JO - Journal of Urology

JF - Journal of Urology

SN - 0022-5347

IS - 6

ER -