Genomic studies of mood disorders - The brain as a muscle?

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Recent genomic studies showing abnormalities in the fibroblast growth factor system in the postmortem brains of people with major depressive disorder support previous indications of a role for growth factors in mood disorders. Similar molecular pathways, volumetric changes, and the effects of exercise on mood suggest a superficial analogy, and perhaps a deeper relationship, between muscle and brain functioning.

Original languageEnglish
Article number215
JournalGenome Biology
Volume6
Issue number4
DOIs
StatePublished - 2005

Fingerprint

emotions
Mood Disorders
brain
genomics
muscle
Muscles
fibroblast growth factors
muscles
Fibroblast Growth Factors
Major Depressive Disorder
Brain
abnormality
growth factors
Intercellular Signaling Peptides and Proteins
exercise
effect

ASJC Scopus subject areas

  • Genetics
  • Cell Biology
  • Ecology, Evolution, Behavior and Systematics

Cite this

Genomic studies of mood disorders - The brain as a muscle? / Niculescu, Alexander.

In: Genome Biology, Vol. 6, No. 4, 215, 2005.

Research output: Contribution to journalArticle

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