Genomic studies of mood disorders - The brain as a muscle?

Research output: Contribution to journalShort survey

12 Scopus citations


Recent genomic studies showing abnormalities in the fibroblast growth factor system in the postmortem brains of people with major depressive disorder support previous indications of a role for growth factors in mood disorders. Similar molecular pathways, volumetric changes, and the effects of exercise on mood suggest a superficial analogy, and perhaps a deeper relationship, between muscle and brain functioning.

Original languageEnglish (US)
Article number215
JournalGenome biology
Issue number4
StatePublished - May 10 2005

ASJC Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics
  • Genetics
  • Cell Biology

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