Genomic variation of adenovirus type 5 isolates recovered from bone marrow transplant recipients

D. H. Webb, A. F. Shields, Kenneth Fife

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

We characterized the genomic variation of adenovirus type 5 isolates recovered from bone marrow transplant recipients in Seattle between 1976 and 1982. By restriction endonuclease analysis, we identified three new adenovirus genomic variants, each associated with a single invasive adenovirus infection. In addition, we were able to obtain suggestive evidence for a nosocomial spread of a particular group of isolates within this population. This study demonstrates that the technique of restriction endonuclease analysis is an important epidemiological tool for investigating viral infections.

Original languageEnglish
Pages (from-to)305-308
Number of pages4
JournalJournal of Clinical Microbiology
Volume25
Issue number2
StatePublished - 1987

Fingerprint

DNA Restriction Enzymes
Adenoviridae
Bone Marrow
Adenoviridae Infections
Virus Diseases
Population
Transplant Recipients

ASJC Scopus subject areas

  • Microbiology
  • Microbiology (medical)

Cite this

Genomic variation of adenovirus type 5 isolates recovered from bone marrow transplant recipients. / Webb, D. H.; Shields, A. F.; Fife, Kenneth.

In: Journal of Clinical Microbiology, Vol. 25, No. 2, 1987, p. 305-308.

Research output: Contribution to journalArticle

@article{8038a0d3b2604910bb3c185767c6de50,
title = "Genomic variation of adenovirus type 5 isolates recovered from bone marrow transplant recipients",
abstract = "We characterized the genomic variation of adenovirus type 5 isolates recovered from bone marrow transplant recipients in Seattle between 1976 and 1982. By restriction endonuclease analysis, we identified three new adenovirus genomic variants, each associated with a single invasive adenovirus infection. In addition, we were able to obtain suggestive evidence for a nosocomial spread of a particular group of isolates within this population. This study demonstrates that the technique of restriction endonuclease analysis is an important epidemiological tool for investigating viral infections.",
author = "Webb, {D. H.} and Shields, {A. F.} and Kenneth Fife",
year = "1987",
language = "English",
volume = "25",
pages = "305--308",
journal = "Journal of Clinical Microbiology",
issn = "0095-1137",
publisher = "American Society for Microbiology",
number = "2",

}

TY - JOUR

T1 - Genomic variation of adenovirus type 5 isolates recovered from bone marrow transplant recipients

AU - Webb, D. H.

AU - Shields, A. F.

AU - Fife, Kenneth

PY - 1987

Y1 - 1987

N2 - We characterized the genomic variation of adenovirus type 5 isolates recovered from bone marrow transplant recipients in Seattle between 1976 and 1982. By restriction endonuclease analysis, we identified three new adenovirus genomic variants, each associated with a single invasive adenovirus infection. In addition, we were able to obtain suggestive evidence for a nosocomial spread of a particular group of isolates within this population. This study demonstrates that the technique of restriction endonuclease analysis is an important epidemiological tool for investigating viral infections.

AB - We characterized the genomic variation of adenovirus type 5 isolates recovered from bone marrow transplant recipients in Seattle between 1976 and 1982. By restriction endonuclease analysis, we identified three new adenovirus genomic variants, each associated with a single invasive adenovirus infection. In addition, we were able to obtain suggestive evidence for a nosocomial spread of a particular group of isolates within this population. This study demonstrates that the technique of restriction endonuclease analysis is an important epidemiological tool for investigating viral infections.

UR - http://www.scopus.com/inward/record.url?scp=0023119284&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023119284&partnerID=8YFLogxK

M3 - Article

C2 - 3029163

AN - SCOPUS:0023119284

VL - 25

SP - 305

EP - 308

JO - Journal of Clinical Microbiology

JF - Journal of Clinical Microbiology

SN - 0095-1137

IS - 2

ER -