Genomic variation of adenovirus type 5 isolates recovered from bone marrow transplant recipients

D. H. Webb, A. F. Shields, K. H. Fife

Research output: Contribution to journalArticle

18 Scopus citations

Abstract

We characterized the genomic variation of adenovirus type 5 isolates recovered from bone marrow transplant recipients in Seattle between 1976 and 1982. By restriction endonuclease analysis, we identified three new adenovirus genomic variants, each associated with a single invasive adenovirus infection. In addition, we were able to obtain suggestive evidence for a nosocomial spread of a particular group of isolates within this population. This study demonstrates that the technique of restriction endonuclease analysis is an important epidemiological tool for investigating viral infections.

Original languageEnglish (US)
Pages (from-to)305-308
Number of pages4
JournalJournal of clinical microbiology
Volume25
Issue number2
StatePublished - Jan 1 1987

ASJC Scopus subject areas

  • Microbiology (medical)

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