Glycogen-rich clear cell carcinoma of the urethra: An ultrastructural study

Meredith T. Hull, Douglas E. Eglen, Thomas Davis, Michael D. Glant, John N. Eble

Research output: Contribution to journalArticle

13 Scopus citations

Abstract

A 49-year-old black woman developed a urethral glycogen-rich clear cell carcinoma. She was treated with anterior pelvic exenteration. The resected lymph nodes, vagina, uterine cervix, endometrium, ovaries, and urinary bladder were free of neoplasm. Histologically the neoplasm consisted of clear cells growing in sheets and occasional papillary structures. In some areas, hobnail cells were present. Ultrastructurally, the cells had apical caps, short microvilli, and complex cell bases, and contained abundant glycogen. These features were identified in one, but not the other of two previously reported cases. Because glycogen-rich clear cell carcinomas of the lower urinary tract do not resemble ultrastructurally mesonephric remnants or carcinomas known to arise from them, these glycogen-rich clear cell carcinomas should not be called me-sonephromas as has been the practice.

Original languageEnglish (US)
Pages (from-to)421-427
Number of pages7
JournalUltrastructural Pathology
Volume11
Issue number4
DOIs
StatePublished - Jan 1 1987

Keywords

  • Clear cell carcinoma
  • Glycogen-rich carcinoma
  • Ultrastructure clear cells
  • Ultrastructure glycogen-rich
  • Ultrastructure urethral carcinoma
  • Urethral carcinoma

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Structural Biology
  • Instrumentation

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