Gross anatomy and morphometric evaluation of the canine lacrimal and third eyelid glands

Shin Ae Park, Ken T. Taylor, Allison L. Zwingenberger, Christopher M. Reilly, Chrisoula A. Toupadakis, Carl Marfurt, Kathryn L. Good, Christopher J. Murphy

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Objective: The lacrimal gland (LG) and the third eyelid gland (TELG) are two intraorbital glands that, in dogs, secrete the aqueous component of the tear film. Despite the central importance of these structures for maintaining ocular surface health, the gross anatomy of the glands remains understudied. We investigated the macroscopic morphometric characteristics of the LG and TELG in three different dog breeds. Procedures: Twenty-six dog heads were dissected to expose the LG and TELG; the length, width, thickness, and weight of each were measured. During the dissections, the relationships between the glands and adjacent ocular structures and the blood and nerve supplies to the LG were photo-documented. Results: The LG had a flat and irregular shape with morphological variations among dogs. The LG was located on the dorsolateral aspect of the globe underneath the orbital ligament. The average length, width, and thickness (SEM) of the LG (mm) were 16.5 ± 0.7, 12.5 ± 0.4, and 2.7 ± 0.1 and of the TELG 10.5 ± 0.6, 11.0 ± 0.3, and 3.3 ± 0.1, respectively. The mean weights (SD) of the LG and TELG (mg) were 315.7 ± 21.1 and 263.3 ± 13.2, respectively. Beagles were observed to have significantly smaller LGs compared to pit bull terriers and pointer mixed-breed dogs. Conclusions: The present study provides detailed normative anatomical and morphometric data for the LG and TELG. These data will aid researchers investigating alterations induced by disease states and should inform strategies for the local delivery of pharmacologic and cellular therapeutics.

Original languageEnglish (US)
Pages (from-to)230-236
Number of pages7
JournalVeterinary Ophthalmology
Volume19
Issue number3
DOIs
StatePublished - May 1 2016

Fingerprint

Nictitating Membrane
lacrimal apparatus
Lacrimal Apparatus
eyelids
Tears
Canidae
Anatomy
dogs
Dogs
Bull Terrier
eyes
Weights and Measures
ligaments
dog breeds
Beagle
Ligaments
Dissection
nerve tissue
researchers
Head

Keywords

  • Beagle
  • Breed difference
  • Dog
  • Intraorbital location
  • Nictitans gland
  • Size

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Park, S. A., Taylor, K. T., Zwingenberger, A. L., Reilly, C. M., Toupadakis, C. A., Marfurt, C., ... Murphy, C. J. (2016). Gross anatomy and morphometric evaluation of the canine lacrimal and third eyelid glands. Veterinary Ophthalmology, 19(3), 230-236. https://doi.org/10.1111/vop.12288

Gross anatomy and morphometric evaluation of the canine lacrimal and third eyelid glands. / Park, Shin Ae; Taylor, Ken T.; Zwingenberger, Allison L.; Reilly, Christopher M.; Toupadakis, Chrisoula A.; Marfurt, Carl; Good, Kathryn L.; Murphy, Christopher J.

In: Veterinary Ophthalmology, Vol. 19, No. 3, 01.05.2016, p. 230-236.

Research output: Contribution to journalArticle

Park, SA, Taylor, KT, Zwingenberger, AL, Reilly, CM, Toupadakis, CA, Marfurt, C, Good, KL & Murphy, CJ 2016, 'Gross anatomy and morphometric evaluation of the canine lacrimal and third eyelid glands', Veterinary Ophthalmology, vol. 19, no. 3, pp. 230-236. https://doi.org/10.1111/vop.12288
Park, Shin Ae ; Taylor, Ken T. ; Zwingenberger, Allison L. ; Reilly, Christopher M. ; Toupadakis, Chrisoula A. ; Marfurt, Carl ; Good, Kathryn L. ; Murphy, Christopher J. / Gross anatomy and morphometric evaluation of the canine lacrimal and third eyelid glands. In: Veterinary Ophthalmology. 2016 ; Vol. 19, No. 3. pp. 230-236.
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