Growth factor regulation of osteogenesis

Stephen B. Trippel

Research output: Chapter in Book/Report/Conference proceedingChapter


Osteogenesis, the creation of bone, underlies all skeletal development and repair. It encompasses the differentiation of cells along specific developmental pathways and the production by these cells of the matrix required to construct, or to reconstruct, bone. The control of this process is, to a large extent, the responsibility of cell signaling molecules that include hormones, growth factors, and cytokines. This chapter reviews some of the factors that participate in regulating the creation of bone at the cellular level.

Original languageEnglish (US)
Title of host publicationBone Regeneration and Repair
Subtitle of host publicationBiology and Clinical Applications
PublisherHumana Press
Number of pages20
ISBN (Print)0896038475, 9780896038479
StatePublished - Dec 1 2005


ASJC Scopus subject areas

  • Medicine(all)

Cite this

Trippel, S. B. (2005). Growth factor regulation of osteogenesis. In Bone Regeneration and Repair: Biology and Clinical Applications (pp. 113-132). Humana Press.