Growth of retinal capillary endothelia using pericyte conditioned medium

H. C. Wong, M. Boulton, J. Marshall, P. Clark

Research output: Contribution to journalArticle

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Abstract

Long-term cultures of bovine retinal capillary endothelial cells (BRCEC) have been established using bovine retinal pericyte conditioned medium (PCM). PCM had greater mitogenic activity on BRCEC than unconditioned medium (P < 0.01). The mitogenic activity of PCM was not cell specific since bovine Tenon's fibroblast conditioned medium also had significant activity. PCM's activity was not enhanced by heparin though it was additive to that of retinal crude extract.

Original languageEnglish (US)
Pages (from-to)1767-1775
Number of pages9
JournalInvestigative Ophthalmology and Visual Science
Volume28
Issue number11
StatePublished - Dec 1 1987

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Pericytes
Vascular Endothelium
Conditioned Culture Medium
Growth
Endothelial Cells
Complex Mixtures
Heparin
Fibroblasts

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience

Cite this

Wong, H. C., Boulton, M., Marshall, J., & Clark, P. (1987). Growth of retinal capillary endothelia using pericyte conditioned medium. Investigative Ophthalmology and Visual Science, 28(11), 1767-1775.

Growth of retinal capillary endothelia using pericyte conditioned medium. / Wong, H. C.; Boulton, M.; Marshall, J.; Clark, P.

In: Investigative Ophthalmology and Visual Science, Vol. 28, No. 11, 01.12.1987, p. 1767-1775.

Research output: Contribution to journalArticle

Wong, HC, Boulton, M, Marshall, J & Clark, P 1987, 'Growth of retinal capillary endothelia using pericyte conditioned medium', Investigative Ophthalmology and Visual Science, vol. 28, no. 11, pp. 1767-1775.
Wong, H. C. ; Boulton, M. ; Marshall, J. ; Clark, P. / Growth of retinal capillary endothelia using pericyte conditioned medium. In: Investigative Ophthalmology and Visual Science. 1987 ; Vol. 28, No. 11. pp. 1767-1775.
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