Growth of retinal capillary endothelia using pericyte conditioned medium

H. C. Wong, M. Boulton, J. Marshall, P. Clark

Research output: Contribution to journalArticle

53 Scopus citations

Abstract

Long-term cultures of bovine retinal capillary endothelial cells (BRCEC) have been established using bovine retinal pericyte conditioned medium (PCM). PCM had greater mitogenic activity on BRCEC than unconditioned medium (P < 0.01). The mitogenic activity of PCM was not cell specific since bovine Tenon's fibroblast conditioned medium also had significant activity. PCM's activity was not enhanced by heparin though it was additive to that of retinal crude extract.

Original languageEnglish (US)
Pages (from-to)1767-1775
Number of pages9
JournalInvestigative Ophthalmology and Visual Science
Volume28
Issue number11
StatePublished - Dec 1 1987

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience

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    Wong, H. C., Boulton, M., Marshall, J., & Clark, P. (1987). Growth of retinal capillary endothelia using pericyte conditioned medium. Investigative Ophthalmology and Visual Science, 28(11), 1767-1775.