Guidelines for the prevention of stroke in patients with stroke and transient ischemic attack: A guideline for healthcare professionals from the American Heart Association/American Stroke Association

Walter N. Kernan, Bruce Ovbiagele, Henry R. Black, Dawn M. Bravata, Marc I. Chimowitz, Michael D. Ezekowitz, Margaret C. Fang, Marc Fisher, Karen L. Furie, Donald V. Heck, S. Claiborne Johnston, Scott E. Kasner, Steven J. Kittner, Pamela H. Mitchell, Michael W. Rich, Dejuran Richardson, Lee H. Schwamm, John A. Wilson

Research output: Contribution to journalArticle

1885 Citations (Scopus)

Abstract

The aim of this updated guideline is to provide comprehensive and timely evidence-based recommendations on the prevention of future stroke among survivors of ischemic stroke or transient ischemic attack. The guideline is addressed to all clinicians who manage secondary prevention for these patients. Evidence-based recommendations are provided for control of risk factors, intervention for vascular obstruction, antithrombotic therapy for cardioembolism, and antiplatelet therapy for noncardioembolic stroke. Recommendations are also provided for the prevention of recurrent stroke in a variety of specific circumstances, including aortic arch atherosclerosis, arterial dissection, patent foramen ovale, hyperhomocysteinemia, hypercoagulable states, antiphospholipid antibody syndrome, sickle cell disease, cerebral venous sinus thrombosis, and pregnancy. Special sections address use of antithrombotic and anticoagulation therapy after an intracranial hemorrhage and implementation of guidelines.

Original languageEnglish (US)
Pages (from-to)2160-2236
Number of pages77
JournalStroke
Volume45
Issue number7
DOIs
StatePublished - Jul 2014

Fingerprint

Transient Ischemic Attack
Stroke
Guidelines
Delivery of Health Care
Intracranial Sinus Thrombosis
Patent Foramen Ovale
Hyperhomocysteinemia
Antiphospholipid Syndrome
Intracranial Hemorrhages
Sickle Cell Anemia
Secondary Prevention
Thoracic Aorta
Venous Thrombosis
Blood Vessels
Survivors
Dissection
Atherosclerosis
Therapeutics
Pregnancy

Keywords

  • AHA Scientific Statements
  • atrial fibrillation
  • carotid stenosis
  • hypertension
  • ischemia
  • ischemic attack, transient
  • prevention
  • stroke

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Clinical Neurology
  • Advanced and Specialized Nursing

Cite this

Guidelines for the prevention of stroke in patients with stroke and transient ischemic attack : A guideline for healthcare professionals from the American Heart Association/American Stroke Association. / Kernan, Walter N.; Ovbiagele, Bruce; Black, Henry R.; Bravata, Dawn M.; Chimowitz, Marc I.; Ezekowitz, Michael D.; Fang, Margaret C.; Fisher, Marc; Furie, Karen L.; Heck, Donald V.; Johnston, S. Claiborne; Kasner, Scott E.; Kittner, Steven J.; Mitchell, Pamela H.; Rich, Michael W.; Richardson, Dejuran; Schwamm, Lee H.; Wilson, John A.

In: Stroke, Vol. 45, No. 7, 07.2014, p. 2160-2236.

Research output: Contribution to journalArticle

Kernan, WN, Ovbiagele, B, Black, HR, Bravata, DM, Chimowitz, MI, Ezekowitz, MD, Fang, MC, Fisher, M, Furie, KL, Heck, DV, Johnston, SC, Kasner, SE, Kittner, SJ, Mitchell, PH, Rich, MW, Richardson, D, Schwamm, LH & Wilson, JA 2014, 'Guidelines for the prevention of stroke in patients with stroke and transient ischemic attack: A guideline for healthcare professionals from the American Heart Association/American Stroke Association', Stroke, vol. 45, no. 7, pp. 2160-2236. https://doi.org/10.1161/STR.0000000000000024
Kernan, Walter N. ; Ovbiagele, Bruce ; Black, Henry R. ; Bravata, Dawn M. ; Chimowitz, Marc I. ; Ezekowitz, Michael D. ; Fang, Margaret C. ; Fisher, Marc ; Furie, Karen L. ; Heck, Donald V. ; Johnston, S. Claiborne ; Kasner, Scott E. ; Kittner, Steven J. ; Mitchell, Pamela H. ; Rich, Michael W. ; Richardson, Dejuran ; Schwamm, Lee H. ; Wilson, John A. / Guidelines for the prevention of stroke in patients with stroke and transient ischemic attack : A guideline for healthcare professionals from the American Heart Association/American Stroke Association. In: Stroke. 2014 ; Vol. 45, No. 7. pp. 2160-2236.
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