Haart improves prognosis in HIV-associated progressive multifocal leukoencephalopathy

David B. Clifford, Constantin Yiannoutsos, M. Glicksman, D. M. Simpson, E. J. Singer, P. J. Piliero, C. M. Marra, G. S. Francis, J. C. McArthur, K. L. Tyler, A. C. Tselis, N. E. Hyslop

Research output: Contribution to journalArticle

214 Citations (Scopus)

Abstract

Introduction of highly active antiretroviral therapy (HAART) has been associated with many changes in the complications of human immunodeficiency virus (HIV) infection. A cohort of 25 HIV patients with progressive multifocal leukoencephalopathy (PML) treated with HAART experienced a median survival of >46 weeks. This is an improvement in prognosis compared with recent historic experience and correlated with HIV RNA viral load reductions. We conclude that current HIV therapy is important in improving the outlook of PML in the setting of HIV.

Original languageEnglish (US)
Pages (from-to)623-625
Number of pages3
JournalNeurology
Volume52
Issue number3
StatePublished - Feb 1999
Externally publishedYes

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Progressive Multifocal Leukoencephalopathy
HIV
Highly Active Antiretroviral Therapy
Virus Diseases
Viral Load
RNA
Survival

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Clifford, D. B., Yiannoutsos, C., Glicksman, M., Simpson, D. M., Singer, E. J., Piliero, P. J., ... Hyslop, N. E. (1999). Haart improves prognosis in HIV-associated progressive multifocal leukoencephalopathy. Neurology, 52(3), 623-625.

Haart improves prognosis in HIV-associated progressive multifocal leukoencephalopathy. / Clifford, David B.; Yiannoutsos, Constantin; Glicksman, M.; Simpson, D. M.; Singer, E. J.; Piliero, P. J.; Marra, C. M.; Francis, G. S.; McArthur, J. C.; Tyler, K. L.; Tselis, A. C.; Hyslop, N. E.

In: Neurology, Vol. 52, No. 3, 02.1999, p. 623-625.

Research output: Contribution to journalArticle

Clifford, DB, Yiannoutsos, C, Glicksman, M, Simpson, DM, Singer, EJ, Piliero, PJ, Marra, CM, Francis, GS, McArthur, JC, Tyler, KL, Tselis, AC & Hyslop, NE 1999, 'Haart improves prognosis in HIV-associated progressive multifocal leukoencephalopathy', Neurology, vol. 52, no. 3, pp. 623-625.
Clifford DB, Yiannoutsos C, Glicksman M, Simpson DM, Singer EJ, Piliero PJ et al. Haart improves prognosis in HIV-associated progressive multifocal leukoencephalopathy. Neurology. 1999 Feb;52(3):623-625.
Clifford, David B. ; Yiannoutsos, Constantin ; Glicksman, M. ; Simpson, D. M. ; Singer, E. J. ; Piliero, P. J. ; Marra, C. M. ; Francis, G. S. ; McArthur, J. C. ; Tyler, K. L. ; Tselis, A. C. ; Hyslop, N. E. / Haart improves prognosis in HIV-associated progressive multifocal leukoencephalopathy. In: Neurology. 1999 ; Vol. 52, No. 3. pp. 623-625.
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