Haematological abnormalities in neonatal necrotizing enterocolitis

Rhonnie Song, Girish C. Subbarao, Akhil Maheshwari

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

Objective: Necrotizing enterocolitis (NEC) is a leading cause of morbidity and mortality in preterm infants born prior to 32 weeks gestation or with a birth weight less than 1500 grams. In this article, we review hematological abnormalities associated with NEC. Methods: A literature search was performed using the databases PubMed, EMBASE, and Scopus, and the electronic archive of abstracts presented at the annual meetings of the Pediatric Academic Societies. Results: Thrombocytopenia, disseminated intravascular coagulation, increased or decreased neutrophil counts, and hemolytic anemia are frequent events in NEC. Conclusions: NEC is associated with several hematological abnormalities, which may play a direct or indirect role in the pathogenesis of gut mucosal injury, and may also carry important prognostic information.

Original languageEnglish (US)
Pages (from-to)14-17
Number of pages4
JournalJournal of Maternal-Fetal and Neonatal Medicine
Volume25
Issue numberSUPPL.4
DOIs
StatePublished - Oct 1 2012

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Keywords

  • Anaemia
  • DIC
  • NEC
  • Neutropaenia
  • Nucleated RBC
  • Thrombocytopenia

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology

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